[头颈部鳞状细胞癌的共聚焦激光内镜检查：一项系统评价]
[Confocal laser endomicroscopy of head and neck squamous cell carcinoma: a systematic review].
作者信息
Sievert Matti, Auberville Marc, Oetter Nicolai, Stelzle Florian, Maier Andreas, Mantsopoulos Konstantinos, Iro Heinrich, Goncalves Miguel
机构信息
Hals-Nasen-Ohrenklinik, Kopf- und Hals-Chirurgie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Deutschland.
Bildverstehen und medizinische Anwendung der künstlichen Intelligenz, Fakultät Informatik, Technische Hochschule Ingolstadt, Deutschland.
出版信息
Laryngorhinootologie. 2021 Nov;100(11):875-881. doi: 10.1055/a-1339-1635. Epub 2021 Jan 5.
OBJECTIVE
Confocal laser endomicroscopy (CLE), with a magnification of up to 1000 ×, offers the possibility to visualize intercellular spaces in vivo. CLE has already established itself in different disciplines. This article gives an overview of the current research on CLE in the diagnosis of the head and neck squamous cell carcinoma.
MATERIAL AND METHODS
Systematic bibliographic research in the following online databases: PubMed, MEDLINE, Thompson Reuters Web of Science, SPIE using the following keywords: confocal laser endomicroscopy, CLE, endomicroscopy, head and neck, larynx. Evaluation of the scientific relevance according to defined criteria.
RESULTS
All studies were analyzed concerning the clinical application, clinical findings, and computer-aided data processing.
CONCLUSIONS
The recently published data suggest that CLE has a high potential to improve the diagnosis of malignant mucosal lesions in the upper aerodigestive tract.
目的
共聚焦激光内镜检查（CLE）放大倍数可达1000倍，能够在体内观察细胞间隙。CLE已在不同学科得到应用。本文概述了CLE在头颈部鳞状细胞癌诊断方面的当前研究情况。
材料与方法
在以下在线数据库进行系统的文献检索：PubMed、MEDLINE、汤森路透科学网、SPIE，使用以下关键词：共聚焦激光内镜检查、CLE、内镜检查、头颈部、喉。根据既定标准评估科学相关性。
结果
对所有研究的临床应用、临床发现及计算机辅助数据处理进行了分析。
结论
最近发表的数据表明，CLE在改善上呼吸道消化道恶性黏膜病变诊断方面具有很大潜力。
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