Frassini Simone, Gupta Shailvi, Granieri Stefano, Cimbanassi Stefania, Sammartano Fabrizio, Scalea Thomas M, Chiara Osvaldo
General Surgery and Trauma Team, ASST Grande Ospedale Metropolitano Niguarda, University of Milan, Milano, Piazza Ospedale Maggiore 3, 20162 Milan, Italy.
Adams Cowley Shock Trauma Center, University of Maryland, 22 S Greene St, Baltimore, MD 21201, USA.
J Clin Med. 2021 Jan 1;10(1):129. doi: 10.3390/jcm10010129.
Pelvic trauma continues to have a high mortality rate despite damage control techniques for bleeding control. The aim of our study was to evaluate how Extra-peritoneal Pelvic Packing (EPP) and Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) impact the efficacy on mortality and hemodynamic impact. We retrospectively evaluated patients who sustained blunt trauma, pelvic fracture and hemodynamic instability from 2002 to 2018. We excluded a concomitant severe brain injury, resuscitative thoracotomy, penetrating trauma and age below 14 years old. The study population was divided in EPP and REBOA Zone III group. Propensity score matching was used to adjust baseline differences and then a one-to-one matched analysis was performed. We selected 83 patients, 10 for group: survival rate was higher in EPP group, but not significantly in each outcome we analyzed (24 h, 7 day, overall). EPP had a significant increase in main arterial pressure after procedure (+20.13 mmHg, < 0.001), but this was not as great as the improvement seen in the REBOA group (+45.10 mmHg, < 0.001). EPP and REBOA are effective and improve hemodynamic status: both are reasonable first steps in a multidisciplinary management. Zone I REBOA may be useful in patients 'in extremis condition' with multiple sites of torso hemorrhage, particularly those in extremis.
尽管有控制出血的损伤控制技术,但骨盆创伤的死亡率仍然很高。我们研究的目的是评估腹膜外骨盆填塞(EPP)和主动脉复苏性血管内球囊阻断术(REBOA)对死亡率和血流动力学的影响效果。我们回顾性评估了2002年至2018年期间遭受钝性创伤、骨盆骨折和血流动力学不稳定的患者。我们排除了伴有严重脑损伤、复苏性开胸手术、穿透性创伤以及年龄低于14岁的患者。研究人群分为EPP组和REBOA III区组。采用倾向评分匹配法调整基线差异,然后进行一对一匹配分析。我们选取了83例患者,每组10例:EPP组的生存率更高,但在我们分析的每个结局(24小时、7天、总体)中差异均无统计学意义。EPP术后主要动脉压显著升高(+20.13 mmHg,P<0.001),但不如REBOA组升高明显(+45.10 mmHg,P<0.001)。EPP和REBOA均有效且能改善血流动力学状态:两者都是多学科管理中合理的首要步骤。I区REBOA可能对有多处躯干出血的“极度危急状态”患者有用,尤其是那些处于极度危急状态的患者。