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Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts.

作者信息

Heberlein U, Tjian R

机构信息

Howard Hughes Medical Institute, Department of Biochemistry, University of California, Berkeley 94720.

出版信息

Nature. 1988 Feb 4;331(6155):410-5. doi: 10.1038/331410a0.

DOI:10.1038/331410a0
PMID:3340187
Abstract

Regulation of transcription during development has been analysed in vitro using extracts derived from Drosophila embryos. Transcription of mutant templates reveals cis-control regions of the alcohol dehydrogenase promoter responsible for temporal regulation. The activity of a trans-acting protein correlates with the profile of alcohol dehydrogenase expression during embryogenesis.

摘要

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