Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts.
作者信息
Heberlein U, Tjian R
机构信息
Howard Hughes Medical Institute, Department of Biochemistry, University of California, Berkeley 94720.
出版信息
Nature. 1988 Feb 4;331(6155):410-5. doi: 10.1038/331410a0.
DOI:10.1038/331410a0
PMID:3340187
Abstract
Regulation of transcription during development has been analysed in vitro using extracts derived from Drosophila embryos. Transcription of mutant templates reveals cis-control regions of the alcohol dehydrogenase promoter responsible for temporal regulation. The activity of a trans-acting protein correlates with the profile of alcohol dehydrogenase expression during embryogenesis.
摘要
Zotero 插件