Lim Jung Sub, Kim Eun Young, Kim Jae Hyun, Yoo Jae-Ho, Yi Kyung Hee, Chae Hyun Wook, Choi Jin-Ho, Kim Ji Young, Hwang Il Tae
Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
Department of Pediatrics, Chosun Universit y S chool of M edicine, Kwangju, Korea.
Ann Pediatr Endocrinol Metab. 2020 Dec;25(4):199-207. doi: 10.6065/apem.2040198.099. Epub 2020 Dec 31.
The Committee on Dyslipidemia of Korean Pediatric and Adolescents of the Korean Society of Pediatric Endocrinology has newly developed evidence-based clinical practice guidelines for dyslipidemia in Korean children and adolescents. These guidelines were formulated with the Grading of Recommendations, which include both the strength of recommendations and the quality of evidence. In the absence of sufficient evidence, conclusions were based on expert opinion. These guidelines are based on the 2011 National Heart, Lung, and Blood Institute Guidelines, which focus on the prevention of cardiovascular disease in children and draw from a comprehensive review of evidence. These guidelines contain the definition of and screening process for dyslipidemia and introduce new dietary methods: the Cardiovascular Health Integrated Lifestyle Diet (CHILD)-1, the CHILD-2-low-density lipoprotein cholesterol, and the CHILD-2-triglyceride. Potential drug therapies for dyslipidemia along with their main effects and doses were also included.
韩国儿科内分泌学会韩国儿童和青少年血脂异常委员会新制定了基于证据的韩国儿童和青少年血脂异常临床实践指南。这些指南采用了推荐分级制定,其中包括推荐强度和证据质量。在缺乏充分证据的情况下,结论基于专家意见。这些指南以2011年美国国立心肺血液研究所指南为基础,该指南侧重于儿童心血管疾病的预防,并借鉴了全面的证据综述。这些指南包含血脂异常的定义和筛查过程,并介绍了新的饮食方法:心血管健康综合生活方式饮食(CHILD)-1、CHILD-2-低密度脂蛋白胆固醇和CHILD-2-甘油三酯。还包括血脂异常的潜在药物治疗及其主要作用和剂量。