碳离子放疗与光子放疗治疗Ⅰ期食管癌的剂量学比较。
Dosimetric Comparison Between Carbon-ion Radiotherapy and Photon Radiotherapy for Stage I Esophageal Cancer.
机构信息
Department of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Japan;
Department of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Japan.
出版信息
In Vivo. 2021 Jan-Feb;35(1):447-452. doi: 10.21873/invivo.12277.
Abstract
BACKGROUND/AIM: The present study aimed to compare the radiation dose distribution of carbon-ion radiotherapy (CIRT) for stage I esophageal cancer with three-dimensional conformal radiotherapy (3DCRT) and volumetric modulated arc therapy (VMAT).
PATIENTS AND METHODS
Fifteen patients with cT1bN0M0 esophageal cancer who received 3DCRT at Kanagawa Cancer Center between January 2014 and April 2019 were enrolled. The dose-volume histogram parameters of the target volume and normal organs planned with CIRT, 3DCRT, and VMAT were evaluated.
RESULTS
The homogeneity index for the target volume of CIRT was significantly lower than that of 3DCRT and VMAT. In addition, the radiation dose of CIRT to the heart, lungs, spinal cord, and skin was significantly lower than that of 3DCRT and VMAT.
CONCLUSION
Favorable dose distributions with CIRT were demonstrated compared with 3DCRT and VMAT for esophageal cancer.
摘要
背景/目的：本研究旨在比较碳离子放疗（CIRT）与三维适形放疗（3DCRT）和容积旋转调强放疗（VMAT）治疗 I 期食管癌的剂量分布。
患者和方法
本研究纳入了 2014 年 1 月至 2019 年 4 月在神奈川癌症中心接受 3DCRT 治疗的 15 例 cT1bN0M0 食管癌患者。评估了 CIRT、3DCRT 和 VMAT 计划的靶区和正常器官的剂量-体积直方图参数。
结果
CIRT 靶区的均匀性指数明显低于 3DCRT 和 VMAT。此外，CIRT 对心脏、肺、脊髓和皮肤的辐射剂量明显低于 3DCRT 和 VMAT。
结论
与 3DCRT 和 VMAT 相比，CIRT 治疗食管癌可获得更好的剂量分布。
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