新生儿坏死性小肠结肠炎的临床特征和结局。

Clinical Spectrum and Outcomes of Neonatal Necrotizing Enterocolitis.

机构信息

Department of General and Oncological Surgery for Children and Adolescents Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland;

Department of Pediatric Hematology and Oncology, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland.

出版信息

In Vivo. 2021 Jan-Feb;35(1):585-591. doi: 10.21873/invivo.12295.

DOI:10.21873/invivo.12295

PMID:33402513

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7880741/

Abstract

BACKGROUND/AIM: The objective of the study was analysis of risk factors associated with outcome of necrotizing enterocolitis (NEC) in infants in a single-center study.

PATIENTS AND METHODS

All consecutive infants hospitalized for NEC over a period of 6 years were retrospectively analyzed for clinical course, infections, treatment and outcome.

RESULTS

Out of 76 patients, surgical management was applied in 56 (53 exploratory laparotomy, three initial peritoneal drain placement) and in 20 there was only a conservative approach. Segmental intestinal resection was performed in 41 patients. Survival from NEC in our cohort was 79%. We found that independent adverse risk factors of outcome of newborns and infants with NEC were gut perforation, infection, abdominal wall erythema, and development of acute kidney injury.

CONCLUSION

We underline the value of both surgical and conservative approach with careful management in this cohort of patients.

摘要

背景/目的：本研究的目的是分析单中心研究中与坏死性小肠结肠炎（NEC）结局相关的危险因素。

患者和方法

对 6 年来因 NEC 住院的所有连续婴儿的临床过程、感染、治疗和结局进行回顾性分析。

结果

76 例患儿中，56 例行手术治疗（53 例行剖腹探查术，3 例初始行腹腔引流术），20 例仅行保守治疗。41 例患儿行肠段切除术。本队列 NEC 的存活率为 79%。我们发现，新生儿和婴儿 NEC 结局的独立不良危险因素是肠穿孔、感染、腹壁红斑和急性肾损伤的发生。

结论

我们强调了在这组患者中，手术和保守治疗方法的价值，以及谨慎的管理。

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新生儿坏死性小肠结肠炎的临床特征和结局。

Clinical Spectrum and Outcomes of Neonatal Necrotizing Enterocolitis.

机构信息

Department of General and Oncological Surgery for Children and Adolescents Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland;

Department of Pediatric Hematology and Oncology, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland.

出版信息

In Vivo. 2021 Jan-Feb;35(1):585-591. doi: 10.21873/invivo.12295.

DOI:10.21873/invivo.12295

PMID:33402513

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7880741/

Abstract

BACKGROUND/AIM: The objective of the study was analysis of risk factors associated with outcome of necrotizing enterocolitis (NEC) in infants in a single-center study.

PATIENTS AND METHODS

All consecutive infants hospitalized for NEC over a period of 6 years were retrospectively analyzed for clinical course, infections, treatment and outcome.

RESULTS

CONCLUSION

We underline the value of both surgical and conservative approach with careful management in this cohort of patients.

摘要

背景/目的：本研究的目的是分析单中心研究中与坏死性小肠结肠炎（NEC）结局相关的危险因素。

患者和方法

对 6 年来因 NEC 住院的所有连续婴儿的临床过程、感染、治疗和结局进行回顾性分析。

结果

结论

我们强调了在这组患者中，手术和保守治疗方法的价值，以及谨慎的管理。

新生儿坏死性小肠结肠炎的临床特征和结局。

Clinical Spectrum and Outcomes of Neonatal Necrotizing Enterocolitis.

机构信息

出版信息

PATIENTS AND METHODS

RESULTS

CONCLUSION

患者和方法

结果

结论

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新生儿坏死性小肠结肠炎的临床特征和结局。

Clinical Spectrum and Outcomes of Neonatal Necrotizing Enterocolitis.

机构信息

出版信息

PATIENTS AND METHODS

RESULTS

CONCLUSION

患者和方法

结果

结论