Department of Oncology and Palliative Medicine, Nordland Hospital, Bodø, Norway;
Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
In Vivo. 2021 Jan-Feb;35(1):649-652. doi: 10.21873/invivo.12304.
BACKGROUND/AIM: The study aimed to evaluate practice changes in the time period of the early wave of the COVID-19 pandemic.
This was a retrospective single institution study. We defined palliative radiotherapy (PRT) initiated before Saturday, March 14 as pre-COVID and PRT initiated later as during-COVID (through June 30).
National COVID-19 recommendations led to a significant decrease in PRT with 10 or more fractions, while re-irradiation and radiotherapy during the final 30 days of life were equally common before and after these recommendations had been issued in March 2020.
Rapid adoption of modified PRT regimens was feasible. However, the challenge of overtreatment in the final phase of the disease, due to inaccurate survival prediction, persisted.
背景/目的:本研究旨在评估 COVID-19 大流行早期阶段的实践变化。
这是一项回顾性单机构研究。我们将周六(3 月 14 日)之前开始的姑息性放疗(PRT)定义为 COVID-19 之前,而周六之后(截至 6 月 30 日)开始的 PRT 定义为 COVID-19 期间。
国家 COVID-19 建议导致接受 10 次或更多次分割的 PRT 显著减少,而在 2020 年 3 月发布这些建议前后,重新放疗和生命最后 30 天的放疗同样常见。
快速采用改良的 PRT 方案是可行的。然而,由于生存预测不准确,导致疾病终末期过度治疗的挑战依然存在。