Guy's and St Thomas' NHS Foundation Trust (GSTT), Medical Oncology, London, UK.
South East London Cancer Alliance, London, UK.
Br J Cancer. 2021 Mar;124(6):1079-1087. doi: 10.1038/s41416-020-01207-7. Epub 2021 Jan 5.
Rapid Diagnostic Clinics (RDC) are being expanded nationally by NHS England. Guy's RDC established a pathway for GPs and internal referrals for patients with symptoms concerning for malignancy not suitable for a site-specific 2WW referral. However, little data assessing the effectiveness of RDC models are available in an English population.
We evaluated all patients referred to Guy's RDC between December 2016 and June 2019 (n = 1341) to assess the rate of cancer diagnoses, frequency of benign conditions and effectiveness of the service.
There were 96 new cancer diagnoses (7.2%): lung (16%), haematological (13%) and colorectal (12%)-with stage IV being most frequent (40%). Median time to definitive cancer diagnosis was 28 days (IQR 15-47) and treatment 56 days (IQR 32-84). In all, 75% were suitable for treatment: surgery (26%), systemic (24%) and radiotherapy (14%). Over 180 serious non-neoplastic conditions were diagnosed (35.8%) of patients with no significant findings in two-third of patients (57.0%).
RDCs provide GPs with a streamlined pathway for patients with complex non-site-specific symptoms that can be challenging for primary care. The 7% rate of cancer diagnosis exceeds many 2WW pathways and a third of patients presented with significant non-cancer diagnoses, which justifies the need for rapid diagnostics. Rapid Diagnostic Centres (RDCs) are being rolled out nationally by NHS England and NHS Improvement as part of the NHS long-term plan. The aim is for a primary care referral pathway that streamlines diagnostics, patient journey, clinical outcomes and patient experience. This pilot study of 1341 patients provides an in-depth analysis of the largest single RDC in England. Cancer was diagnosed in 7% of patients and serious non-cancer conditions in 36%-justifying the RDC approach in vague symptom patients.
英国国民保健署正在全国范围内扩大快速诊断诊所(RDC)的规模。盖伊的 RDC 为全科医生和内部转诊患者建立了一条途径,这些患者的症状令人担忧,但不适合特定部位的 2WW 转诊。然而,在英国人群中,几乎没有关于 RDC 模型有效性的评估数据。
我们评估了 2016 年 12 月至 2019 年 6 月期间转诊到盖伊 RDC 的所有患者(n=1341),以评估癌症诊断率、良性疾病的频率和服务的有效性。
共有 96 例新发癌症诊断(7.2%):肺癌(16%)、血液系统(13%)和结直肠(12%)-其中最常见的是 IV 期(40%)。明确癌症诊断的中位时间为 28 天(IQR 15-47),治疗时间为 56 天(IQR 32-84)。在所有患者中,75%适合治疗:手术(26%)、全身治疗(24%)和放疗(14%)。超过 180 例严重非肿瘤疾病被诊断(35.8%),三分之二的患者无明显发现(57.0%)。
RDC 为全科医生提供了一条针对具有复杂非特定部位症状的患者的简化途径,这些症状对初级保健具有挑战性。7%的癌症诊断率超过了许多 2WW 途径,三分之一的患者有显著的非癌症诊断,这证明了快速诊断的必要性。英国国民保健署和 NHS 改善正在全国范围内推出快速诊断中心(RDC),作为 NHS 长期计划的一部分。目的是建立一个以初级保健为基础的转诊途径,以简化诊断、患者旅程、临床结果和患者体验。这项对 1341 名患者的试点研究提供了对英国最大的单个 RDC 的深入分析。7%的患者被诊断患有癌症,36%的患者被诊断患有严重的非癌症疾病-证明了 RDC 方法在症状模糊的患者中的合理性。