Xu S, Kang Ybj, Soeharno H, Yeo Nem
Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
Malays Orthop J. 2020 Nov;14(3):194-197. doi: 10.5704/MOJ.2011.033.
Marjolin's ulcer is a rare and often overlooked diagnosis which can be encountered by a variety of specialities. Majority of the literatures describe long latency period of 11 to 75 years. The authors present two unusual cases of rapid progression to Marjolin's ulcer in patients with previously negative biopsy 8- and 10-month prior. This highlights the importance for clinicians to have a high degree of suspicion when encountered with any non-healing wound, especially one who's symptomatology and morphological features have undergone an acute change. Even with previous negative biopsy, patients should still be followed-up closely and clinicians should not hesitate to perform re-biopsy if the suspicion arises.
马乔林溃疡是一种罕见且常被忽视的诊断，多个专业领域都可能遇到。大多数文献描述其潜伏期长达11至75年。本文作者介绍了两例不寻常的病例，患者在之前8个月和10个月活检结果为阴性的情况下，迅速发展为马乔林溃疡。这凸显了临床医生在遇到任何不愈合伤口时保持高度怀疑的重要性，尤其是那些症状和形态特征发生急性变化的伤口。即使之前活检结果为阴性，仍应密切随访患者，若产生怀疑，临床医生应毫不犹豫地进行再次活检。
