Yale AIDS Prevention Training Program (Y-APT), Center for Interdisciplinary Research on AIDS (CIRA), Yale University, 135 College St. Suite 200, New Haven, CT, 06510, USA.
College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, Tampa, FL, 33612, USA.
AIDS Behav. 2021 Jul;25(7):2240-2251. doi: 10.1007/s10461-020-03152-1. Epub 2021 Jan 5.
HIV testing/counseling is a critical point during which non-clinical staff could intervene, discuss and/or refer clients for pre-exposure prophylaxis (PrEP). This analysis investigated the contextual factors affecting PrEP implementation within HIV testing sites. Two generalized linear mixed models were conducted to estimate PrEP implementation as a function of constructs from the Consolidated Framework for Implementation Research (CFIR). Qualitative interviews were analyzed thematically. Data integration occurred via joint analysis and triangulation. Constructs from the CFIR domain Characteristics of Individuals did not predict PrEP implementation when controlling for demographic characteristics; qualitative data signaled divergent findings in PrEP knowledge. Within the CFIR domains Inner and Outer Settings, relevant priority and available resources predicted PrEP implementation; qualitative data confirmed the importance of available resources and provided insight into the impact of cosmopolitanism and leadership. Addressing the contextual factors that affect PrEP implementation may help HIV testing staff to better implement PrEP programs.
艾滋病毒检测/咨询是一个关键的时刻，非临床工作人员可以在这个时候进行干预，讨论和/或转介客户进行暴露前预防（PrEP）。本分析研究了影响艾滋病毒检测点实施 PrEP 的环境因素。进行了两个广义线性混合模型，以估计 PrEP 的实施情况，这是根据实施研究综合框架（CFIR）的结构来进行的。对定性访谈进行了主题分析。通过联合分析和三角测量进行数据集成。在控制人口统计学特征的情况下，来自 CFIR 个体特征领域的结构并不能预测 PrEP 的实施；定性数据表明 PrEP 知识存在不同的发现。在 CFIR 领域的内部和外部环境中，相关的优先级和可用资源预测 PrEP 的实施；定性数据证实了可用资源的重要性，并深入了解了世界主义和领导力的影响。解决影响 PrEP 实施的环境因素可能有助于艾滋病毒检测人员更好地实施 PrEP 计划。
