• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Genetic Variants of SARS-CoV-2-What Do They Mean?

作者信息

Lauring Adam S, Hodcroft Emma B

机构信息

Division of Infectious Diseases, Department of Internal Medicine and Department of Microbiology and Immunology, University of Michigan, Ann Arbor.

Institute of Social and Preventive Medicine, University of Bern, Switzerland.

出版信息

JAMA. 2021 Feb 9;325(6):529-531. doi: 10.1001/jama.2020.27124.

DOI:10.1001/jama.2020.27124
PMID:33404586
Abstract
摘要

相似文献

1
Genetic Variants of SARS-CoV-2-What Do They Mean?新型冠状病毒2019(SARS-CoV-2)的基因变异——它们意味着什么?
JAMA. 2021 Feb 9;325(6):529-531. doi: 10.1001/jama.2020.27124.
2
Novavax offers first evidence that COVID vaccines protect people against variants.诺瓦瓦克斯公司提供了首个证据,证明新冠疫苗可保护人们抵御病毒变种。
Nature. 2021 Feb;590(7844):17. doi: 10.1038/d41586-021-00268-9.
3
How to redesign COVID vaccines so they protect against variants.如何重新设计新冠疫苗以使其能抵御变异毒株。
Nature. 2021 Feb;590(7844):15-16. doi: 10.1038/d41586-021-00241-6.
4
Infection, recovery and re-infection of farmed mink with SARS-CoV-2.养殖水貂中 SARS-CoV-2 的感染、恢复和再感染。
PLoS Pathog. 2021 Nov 15;17(11):e1010068. doi: 10.1371/journal.ppat.1010068. eCollection 2021 Nov.
5
Symptomatic SARS-CoV-2 infections after full schedule BNT162b2 vaccination in seropositive healthcare workers: a case series from a single institution.血清阳性医护人员完成 BNT162b2 全程接种后出现有症状的 SARS-CoV-2 感染:来自单一机构的病例系列研究。
Emerg Microbes Infect. 2021 Dec;10(1):1254-1256. doi: 10.1080/22221751.2021.1942230.
6
Sieve analysis to understand how SARS-CoV-2 diversity can impact vaccine protection.通过筛析法了解严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的多样性如何影响疫苗保护效果。
PLoS Pathog. 2021 Mar 25;17(3):e1009406. doi: 10.1371/journal.ppat.1009406. eCollection 2021 Mar.
7
How 'killer' T cells could boost COVID immunity in face of new variants.面对新冠病毒新变种,“杀手”T细胞如何增强对新冠的免疫力。
Nature. 2021 Feb;590(7846):374-375. doi: 10.1038/d41586-021-00367-7.
8
Heavily mutated Omicron variant puts scientists on alert.高度变异的奥密克戎毒株使科学家们警觉起来。
Nature. 2021 Dec;600(7887):21. doi: 10.1038/d41586-021-03552-w.
9
Neutralizing SARS-CoV-2.中和 SARS-CoV-2
Elife. 2020 Dec 15;9:e64496. doi: 10.7554/eLife.64496.
10
Evolving threat.不断演变的威胁。
Science. 2021 Aug 20;373(6557):844-849. doi: 10.1126/science.373.6557.844.

引用本文的文献

1
Diabetes Mellitus, a Leading Comorbidity in COVID-19: an Insight on Pathophysiology, Molecular Interactions, and Comprehensive Management.糖尿病,COVID-19中的主要合并症:对病理生理学、分子相互作用及综合管理的见解
Curr Microbiol. 2025 Jul 16;82(9):388. doi: 10.1007/s00284-025-04369-w.
2
Evolving fitness and immune escape: a retrospective analysis of SARS-CoV-2 spike protein (2020-2024) using protein language model.不断演变的适应性与免疫逃逸:使用蛋白质语言模型对严重急性呼吸综合征冠状病毒2刺突蛋白(2020 - 2024年)的回顾性分析
Front Immunol. 2025 Jun 18;16:1576414. doi: 10.3389/fimmu.2025.1576414. eCollection 2025.
3
Comparison of Three Commercial ELISA Kits for Detection of Antibodies Against SARS-CoV-2 in Serum Samples from Different Animal Species.
三种用于检测不同动物物种血清样本中抗 SARS-CoV-2 抗体的商用 ELISA 试剂盒的比较
Viruses. 2025 May 16;17(5):716. doi: 10.3390/v17050716.
4
Epitope-based Multi-variant SARS-Cov-2 Vaccine Design: Shared Epitopes Among the Natural SARS-Cov-2 Spike Glycoprotein and 5 of its Variants (D614G, α, β, γ, δ) with High Binding Affinity to Human Leukocyte Antigen (HLA) Class II Molecules.基于表位的多变体SARS-CoV-2疫苗设计:天然SARS-CoV-2刺突糖蛋白及其5种变体(D614G、α、β、γ、δ)之间的共享表位,这些变体与人类白细胞抗原(HLA)II类分子具有高结合亲和力。
J Immunol Sci. 2021 Oct 29;5(4):9-14. doi: 10.29245/2578-3009/2021/4.1223.
5
Intersecting SARS-CoV-2 spike mutations and global vaccine efficacy against COVID-19.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)刺突蛋白突变与全球新冠疫苗有效性的交叉分析
Front Immunol. 2025 Mar 7;16:1435873. doi: 10.3389/fimmu.2025.1435873. eCollection 2025.
6
Estimation and Hypothesis Testing of Strain-Specific Vaccine Efficacy With Missing Strain Types With Application to a COVID-19 Vaccine Trial.针对存在缺失毒株类型情况的特定毒株疫苗效力的估计与假设检验及其在一项新冠疫苗试验中的应用
Stat Med. 2025 Mar 15;44(6):e10345. doi: 10.1002/sim.10345.
7
Genomic Diversity and Evolution of Identified SARS-CoV-2 Variants in Iraq.伊拉克已鉴定的新冠病毒变异株的基因组多样性与进化
Pathogens. 2024 Nov 29;13(12):1051. doi: 10.3390/pathogens13121051.
8
Immunogenicity of two-dose sinopharm BBIB-CorV vaccine in Morocco: One-year follow-up and neutralizing activity against severe acute respiratory syndrome coronavirus 2 variants of concern.摩洛哥两剂国药 BBIB-CorV 疫苗的免疫原性:一年随访及对严重急性呼吸综合征冠状病毒 2 关切变异株的中和活性。
Immun Inflamm Dis. 2024 Nov;12(11):e1359. doi: 10.1002/iid3.1359.
9
Dynamics of an SVEIR transmission model with protection awareness and two strains.具有防护意识和两种毒株的SVEIR传播模型的动力学
Infect Dis Model. 2024 Oct 10;10(1):207-228. doi: 10.1016/j.idm.2024.10.001. eCollection 2025 Mar.
10
Comparison of the effectiveness of awake-prone positioning and high-flow nasal oxygen in patients with COVID-19-related acute respiratory failure between different waves.不同波次的 COVID-19 相关急性呼吸衰竭患者中清醒俯卧位通气与高流量鼻氧疗效果的比较。
Crit Care Sci. 2024 Oct 21;36:e20240065en. doi: 10.62675/2965-2774.20240065-en. eCollection 2024.