小分子桦木醇对固醇调节元件结合蛋白的抑制作用可改善高脂血症和胰岛素抵抗，并减少动脉粥样硬化斑块。 - Suppr

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超能文献

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques.

作者信息

Tang Jing-Jie, Li Jia-Gui, Qi Wei, Qiu Wen-Wei, Li Pei-Shan, Li Bo-Liang, Song Bao-Liang

出版信息

Cell Metab. 2021 Jan 5;33(1):222. doi: 10.1016/j.cmet.2020.11.013.

DOI:10.1016/j.cmet.2020.11.013

PMID:33406401

Abstract

摘要

相似文献

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques.小分子桦木醇对固醇调节元件结合蛋白的抑制作用可改善高脂血症和胰岛素抵抗，并减少动脉粥样硬化斑块。

Cell Metab. 2021 Jan 5;33(1):222. doi: 10.1016/j.cmet.2020.11.013.

Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques.小分子桦木酸通过抑制 SREBP 改善高脂血症和胰岛素抵抗并减少动脉粥样硬化斑块。

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Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.二十二碳六烯酸通过激活AMP活化蛋白激酶抑制固醇调节元件结合蛋白-1c（SREBP-1c）的蛋白水解加工。

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Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway.桦木醇通过 SIRT1/AMPK 信号通路缓解乙醇诱导的酒精性肝损伤。

Pharmacol Res. 2016 Mar;105:1-12. doi: 10.1016/j.phrs.2015.12.022. Epub 2016 Jan 15.

Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.协调调控肝 FoxO1、PGC-1α 和 SREBP-1c 有助于胰岛素作用和抵抗。

Cell Signal. 2018 Mar;43:62-70. doi: 10.1016/j.cellsig.2017.12.005. Epub 2017 Dec 18.

Down-regulated of SREBP-1 in circulating leukocyte is a risk factor for atherosclerosis: a case control study.循环白细胞中 SREBP-1 下调是动脉粥样硬化的危险因素：一项病例对照研究。

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Correction: Praeruptorin B improves diet-induced hyperlipidemia and alleviates insulin resistance regulating SREBP signaling pathway.更正：前胡素B可改善饮食诱导的高脂血症并通过调节SREBP信号通路减轻胰岛素抵抗。

RSC Adv. 2019 Feb 19;9(11):6101. doi: 10.1039/c9ra90010a. eCollection 2019 Feb 18.

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Zhongguo Zhong Xi Yi Jie He Za Zhi. 2015 Mar;35(3):320-6.

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