Ryan A D, Goldberg I, O'Brien B M, MacLeod A M
Microsurgery Research Centre, St. Vincent's Hospital, Melbourne, Australia.
Plast Reconstr Surg. 1988 Mar;81(3):414-7. doi: 10.1097/00006534-198803000-00018.
In this study, 100 rabbits were used to assess the efficacy of five different methods of microvascular anastomosis where a vessel diameter discrepancy of 5:1 existed. The inferior vena cava of the rabbit was used as a graft in the femoral artery. In 50 percent of the rabbits the graft was reversed to assess the effects on flow. When explored between 7 and 10 days after anastomosis, an overall patency rate of 96 percent was recorded. Three grafts were not patent in the reversed group and one was not patent in the nonreversed group. There was no significant statistical difference in patency rates between any of the groups, as calculated by the Fisher's exact probability test. The tapered end-to-end and side-to-end anastomoses were found to be the most rapid and simplest methods to perform.
在本研究中，使用100只兔子来评估五种不同微血管吻合方法的疗效，这些方法用于存在5:1血管直径差异的情况。兔的下腔静脉被用作股动脉的移植物。50%的兔子使用了逆向移植物以评估对血流的影响。在吻合后7至10天进行探查时，记录的总体通畅率为96%。逆向组中有3个移植物未通畅，非逆向组中有1个未通畅。通过Fisher精确概率检验计算，各实验组间的通畅率无显著统计学差异。发现锥形端端吻合和端侧吻合是实施起来最快捷、最简单的方法。
