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终末期肾病按病种付费制度实施后血液透析导管管理的变化。

Changes in hemodialysis catheter management after introduction of the end-stage renal disease prospective payment system.

机构信息

Chronic Disease Research Group, Hennepin Healthcare Research Institute, 701 Park Ave., Suite S2.100, Minneapolis, MN, 55415, USA.

Genentech, Inc., South San Francisco, CA, USA.

出版信息

BMC Nephrol. 2021 Jan 6;22(1):8. doi: 10.1186/s12882-020-02222-9.

Abstract

BACKGROUND

We investigated whether implementation of the end-stage renal disease prospective payment system (ESRD PPS) was associated with changes in thrombolytic therapy use and other aspects of catheter management in hemodialysis (HD) patients.

METHODS

Using quarterly, period prevalent cohorts of patients undergoing maintenance HD with a catheter in the US Renal Data System (2008-2015), we studied rates of claims for within- and outside-HD-unit thrombolytic use, and thrombus/fibrin sheath removal, and rates of delayed HD treatment after ESRD PPS implementation, January 1, 2011. Associations between PPS implementation and change in trend of rates of each outcome were assessed using covariate-adjusted Poisson regression, using a piecewise linear function for quarter-time (with breakpoint at PPS implementation).

RESULTS

Among an average of 69,428 quarterly catheter users, rates of claims for within-HD-unit thrombolytic use declined from 236.6 (Q1-2008) to 81.4 (Q4-2012) per 100 person-years (P < 0.0001, PPS association with change in trend); rates of claims for thrombus/fibrin sheath removal procedures increased from 3.9 (Q1-2008) to 8.8 (Q3-2015) per 100 person-years (P = 0.0001, PPS association with change in trend). Rates of delayed HD treatment increased from 1.6 (Q2-2008) to 2.3 (Q3-2015) per patient-quarter, although PPS implementation was associated with a decrease in this rising trend (1.6% increase per quarter pre-PPS, 1.2% post-PPS; P < 0.0001, change in trend).

CONCLUSIONS

After PPS implementation, thrombolytic use decreased and thrombus/fibrin sheath removal increased. The increasing trend in delayed HD treatment appeared to slow after PPS implementation, but delayed sessions continued to increase year over year for unclear reasons.

摘要

背景

我们研究了终末期肾病前瞻性支付系统(ESRD PPS)的实施是否与血液透析(HD)患者溶栓治疗的使用和导管管理的其他方面的变化有关。

方法

使用美国肾脏数据系统(2008-2015 年)中每季度、期间普遍存在的接受维持性 HD 治疗并带有导管的患者队列,我们研究了在 ESRD PPS 实施后(2011 年 1 月 1 日),HD 单元内和单元外溶栓使用、血栓/纤维鞘去除的索赔率,以及 ESRD PPS 实施后 HD 治疗延迟的发生率。使用协变量调整泊松回归评估 PPS 实施与每种结局趋势变化之间的关联,使用季度时间的分段线性函数(在 PPS 实施处有一个断点)。

结果

在平均 69428 名季度导管使用者中,HD 单元内溶栓使用的索赔率从 2008 年第 1 季度的 236.6(每 100 人年)下降到 2012 年第 4 季度的 81.4(每 100 人年)(P < 0.0001,PPS 与趋势变化相关);血栓/纤维鞘去除程序的索赔率从 2008 年第 1 季度的 3.9(每 100 人年)增加到 2015 年第 3 季度的 8.8(每 100 人年)(P = 0.0001,PPS 与趋势变化相关)。每个患者季度的 HD 治疗延迟发生率从 2008 年第 2 季度的 1.6 增加到 2015 年第 3 季度的 2.3,但 PPS 实施与该上升趋势的下降相关(PPS 前每季度增加 1.6%,PPS 后增加 1.2%;P < 0.0001,趋势变化)。

结论

在 PPS 实施后,溶栓治疗减少,血栓/纤维鞘去除增加。在 PPS 实施后,HD 治疗延迟的上升趋势似乎有所放缓,但延迟治疗仍在继续逐年增加,原因尚不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50b5/7788942/f639e6d44d33/12882_2020_2222_Fig1_HTML.jpg

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