Aberle D R, Gamsu G, Ray C S, Feuerstein I M
Department of Radiology, University of California, San Francisco.
Radiology. 1988 Mar;166(3):729-34. doi: 10.1148/radiology.166.3.3340770.
Twenty-nine subjects with occupational asbestos exposure and clinical asbestosis were examined with high-resolution computed tomography (HRCT) to determine its sensitivity, relative to that of conventional computed tomography (CT), for detection of benign asbestos-related disease. Thin-section HRCT scans were obtained at five discrete levels through the mid and lower thorax in both prone and supine positions. The same technique was used in 34 age-similar control patients. Parenchymal abnormalities were seen most frequently in the posterior portion of the lung bases in the asbestos-exposed subjects. HRCT prone scans enabled basal structural abnormalities to be reliably distinguished from gravity-related physiologic phenomena in 25 asbestos-exposed subjects. HRCT was more sensitive than CT in detection of both pleural and parenchymal fibrosis. In subjects with clinical asbestosis, HRCT demonstrated parenchymal abnormality in 96%, compared with 83% for CT. Similarly, pleural thickening was shown in 100% of subjects at HRCT, compared with 93% at CT. HRCT could be an important adjunct in the evaluation of asbestos-related pleuroparenchymal fibrosis. An HRCT study including prone scans is a sensitive, reliable means of detecting thoracic abnormalities in asbestos-exposed individuals.
对29名职业性接触石棉且患有临床石棉肺的受试者进行了高分辨率计算机断层扫描（HRCT），以确定其相对于传统计算机断层扫描（CT）在检测良性石棉相关疾病方面的敏感性。在俯卧位和仰卧位通过胸部中下部的五个离散层面获取薄层HRCT扫描。34名年龄相仿的对照患者采用相同技术进行扫描。在接触石棉的受试者中，肺实质异常最常见于肺底部后部。HRCT俯卧位扫描能够在25名接触石棉的受试者中可靠地将基底结构异常与重力相关的生理现象区分开来。HRCT在检测胸膜和肺实质纤维化方面比CT更敏感。在患有临床石棉肺的受试者中，HRCT显示肺实质异常的比例为96%，而CT为83%。同样，HRCT显示100%的受试者有胸膜增厚，而CT为93%。HRCT可能是评估石棉相关胸膜肺实质纤维化的重要辅助手段。一项包括俯卧位扫描的HRCT研究是检测接触石棉个体胸部异常的敏感、可靠方法。
