Cassell Kelsie, Davis J Lucian, Berkelman Ruth
Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Pulmonary, Critical Care, and Sleep Medicine Section, Yale School of Medicine, New Haven, CT, USA.
Pneumonia (Nathan). 2021 Jan 6;13(1):2. doi: 10.1186/s41479-020-00080-5.
Due to similarities in initial disease presentation, clinicians may be inclined to repeatedly test community-acquired pneumonia cases for COVID-19 before recognizing the need to test for Legionnaires' disease. Legionnaires' disease is an illness characterized by pneumonia that has a summer/early fall seasonality due to favorable conditions for Legionella growth and exposure. Legionella proliferate in warm water environments and stagnant sections of indoor plumbing and cooling systems. During the ongoing pandemic crisis, exposures to aerosolized water from recently reopened office or retail buildings should be considered as an epidemiologic risk factor for Legionella exposure and an indication to test. The majority of Legionnaires' disease cases occurring each year are not diagnosed, and some experts recommend that all patients hospitalized with community-acquired pneumonia without a known etiology be tested for Legionella infection. Proper diagnosis can increase the likelihood of appropriate and timely antibiotic treatment, identify potential clusters of disease, and facilitate source attribution.
由于初始疾病表现相似,临床医生可能倾向于在认识到需要检测军团菌病之前,对社区获得性肺炎病例反复进行新冠病毒检测。军团菌病是一种以肺炎为特征的疾病,由于有利于军团菌生长和接触的条件,其发病具有夏季/初秋季节性。军团菌在温水环境以及室内管道和冷却系统的停滞区域中繁殖。在当前的大流行危机期间,接触最近重新开放的办公或零售建筑中雾化的水应被视为军团菌接触的流行病学危险因素和检测指征。每年发生的大多数军团菌病病例未得到诊断,一些专家建议对所有因社区获得性肺炎住院且病因不明的患者进行军团菌感染检测。正确的诊断可以增加适当及时使用抗生素治疗的可能性,识别潜在的疾病聚集,并有助于溯源。