• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

莱姆性心脏病:获得性三度房室传导阻滞的一个可逆病因。

Lyme Carditis: A Reversible Cause of Acquired Third-Degree AV Block.

机构信息

Department of Internal Medicine, NYC Health+Hospitals/Metropolitan, New York City, NY, USA.

Department of Medicine, Obafemi Awolowo University, Ile-Ife, Ile-Ife, Osun State, Nigeria.

出版信息

Am J Case Rep. 2021 Jan 7;22:e927885. doi: 10.12659/AJCR.927885.

DOI:10.12659/AJCR.927885
PMID:33408318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7797605/
Abstract

BACKGROUND Lyme borreliosis, caused by spirochetes of the Borrelia burgdorferi genospecies complex, is the most commonly reported tickborne infection in North America and those infected may present with cutaneous, cardiac, articular, and neuropsychiatric abnormalities. The protean nature of many of its clinical manifestations presents a diagnostic conundrum. Lyme disease can affect the heart, albeit rarely, with cardiac abnormalities usually manifesting as varying degrees of heart block or arrhythmias. CASE REPORT We present a case of complete heart block in a young man who participated in outdoor activities in a Lyme-endemic area and developed fatigue and palpitations weeks after a flu-like illness. He noticed that his heart rate was low; he had an intermediate suspicious index in Lyme carditis (SILC) score with positive Lyme serologies. His initial electrocardiogram when he presented to the emergency department showed a complete heart block. In this case, he was successfully managed with intravenous ceftriaxone, amoxicillin, and a transcutaneous pacemaker, obviating the need for a permanent pacemaker. CONCLUSIONS Electrocardiographic changes such as heart block and arrhythmias with or without symptoms may be the initial manifestation of Lyme carditis in a patient who may or may not remember a tick bite or have a typical skin rash. The SILC score may assist in recognizing these cases and prompt initiation of antibiotics usually leads to the resolution of these electrocardiographic abnormalities and symptoms that may be present.

摘要

背景

莱姆病是由伯氏疏螺旋体复合种群的螺旋体引起的,是北美最常报告的蜱传感染病,感染后可能出现皮肤、心脏、关节和神经精神异常。其许多临床表现的多变性质构成了诊断难题。莱姆病虽罕见,但可影响心脏,其心脏异常通常表现为不同程度的心脏传导阻滞或心律失常。

病例报告

我们报告了一例年轻男性病例,该男性在莱姆病流行地区参加户外活动后出现疲劳和心悸,在流感样疾病后数周出现。他注意到自己的心率较低;莱姆心脏病(SILC)评分中的中间可疑指数阳性,血清学检测为阳性。他在急诊科就诊时的初始心电图显示完全性心脏传导阻滞。在这种情况下,他成功地接受了静脉注射头孢曲松、阿莫西林和经皮起搏器治疗,避免了永久性起搏器的需要。

结论

心脏传导阻滞和心律失常等心电图变化,无论有无症状,可能是莱姆心脏病患者的初始表现,这些患者可能记得或不记得被蜱叮咬,也可能没有典型皮疹。SILC 评分可能有助于识别这些病例,通常抗生素的早期应用可导致这些心电图异常和可能存在的症状得到缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/85151e6fe1ca/amjcaserep-22-e927885-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/1312aab3eeb8/amjcaserep-22-e927885-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/070e1fc0bcdb/amjcaserep-22-e927885-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/85151e6fe1ca/amjcaserep-22-e927885-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/1312aab3eeb8/amjcaserep-22-e927885-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/070e1fc0bcdb/amjcaserep-22-e927885-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b0/7797605/85151e6fe1ca/amjcaserep-22-e927885-g003.jpg

相似文献

1
Lyme Carditis: A Reversible Cause of Acquired Third-Degree AV Block.莱姆性心脏病:获得性三度房室传导阻滞的一个可逆病因。
Am J Case Rep. 2021 Jan 7;22:e927885. doi: 10.12659/AJCR.927885.
2
First case report of inducible heart block in Lyme disease and an update of Lyme carditis.首例莱姆病诱导性心脏传导阻滞病例报告及莱姆性心肌炎更新
BMC Infect Dis. 2019 May 16;19(1):428. doi: 10.1186/s12879-019-4025-0.
3
Chest palpitations in a teenager as an unusual presentation of Lyme disease: case report.青少年胸痛为莱姆病的不常见表现:病例报告。
BMC Infect Dis. 2020 Oct 7;20(1):730. doi: 10.1186/s12879-020-05438-0.
4
Suspicious index in Lyme carditis: Systematic review and proposed new risk score.莱姆病性心肌炎的可疑指标:系统评价及新风险评分建议
Clin Cardiol. 2018 Dec;41(12):1611-1616. doi: 10.1002/clc.23102. Epub 2018 Nov 26.
5
Lyme carditis: a reversible cause of complete atrioventricular block.莱姆病性心脏炎:完全性房室传导阻滞的可逆病因。
J R Coll Physicians Edinb. 2010 Jun;40(2):121-2. doi: 10.4997/JRCPE.2010.207.
6
[Total atrioventricular block following a tick bite].[蜱叮咬后发生完全性房室传导阻滞]
Ned Tijdschr Geneeskd. 2007 Sep 1;151(35):1941-4.
7
Lyme carditis presenting as sick sinus syndrome.表现为病态窦房结综合征的莱姆病性心脏炎。
J Electrocardiol. 2020 Mar-Apr;59:65-67. doi: 10.1016/j.jelectrocard.2020.01.007. Epub 2020 Jan 25.
8
Reversible high-grade atrioventricular block with septal myocardial edema in Lyme carditis.莱姆性心肌炎致可逆性高度房室传导阻滞伴间隔心肌水肿。
Herzschrittmacherther Elektrophysiol. 2022 Sep;33(3):327-329. doi: 10.1007/s00399-022-00879-3. Epub 2022 Jun 23.
9
A case of reversible third-degree AV block due to Lyme carditis.一例由莱姆病性心肌炎导致的可逆性三度房室传导阻滞病例。
J Electrocardiol. 2016 Jul-Aug;49(4):519-21. doi: 10.1016/j.jelectrocard.2016.05.006. Epub 2016 May 12.
10
Lyme carditis: sequential electrocardiographic changes in response to antibiotic therapy.莱姆心炎:抗生素治疗应答中的心电图连续变化。
Int J Cardiol. 2009 Oct 2;137(2):167-71. doi: 10.1016/j.ijcard.2008.05.028. Epub 2008 Aug 5.

引用本文的文献

1
Associations of Atrioventricular Blocks and Other Arrhythmias in Patients with Lyme Carditis: A Systematic Review and Meta-Analysis.莱姆病性心肌炎患者房室传导阻滞及其他心律失常的关联:一项系统评价和荟萃分析
J Cardiovasc Dev Dis. 2024 Apr 23;11(5):131. doi: 10.3390/jcdd11050131.
2
Management of Complete Heart Block in a Pregnant Woman with Systemic Lupus Erythematosus-Associated Complications: Treatment Considerations and Pitfalls.系统性红斑狼疮相关并发症孕妇完全性心脏阻滞的管理:治疗注意事项及陷阱。
Medicina (Kaunas). 2022 Dec 31;59(1):88. doi: 10.3390/medicina59010088.
3
Inherited and Acquired Rhythm Disturbances in Sick Sinus Syndrome, Brugada Syndrome, and Atrial Fibrillation: Lessons from Preclinical Modeling.

本文引用的文献

1
Lyme carditis atrioventricular block: management strategies.
Europace. 2019 Aug 1;21(8):1280-1282. doi: 10.1093/europace/euz051.
2
Diagnosis and Treatment of Lyme Carditis: JACC Review Topic of the Week.莱姆心炎的诊断与治疗:美国心脏病学会杂志(JACC)本周专题
J Am Coll Cardiol. 2019 Feb 19;73(6):717-726. doi: 10.1016/j.jacc.2018.11.035.
3
Systematic Approach to the Diagnosis and Treatment of Lyme Carditis and High-Degree Atrioventricular Block.莱姆病性心肌炎和高度房室传导阻滞的诊断与治疗的系统方法
遗传性和获得性窦房结综合征、Brugada 综合征和心房颤动中的节律紊乱:临床前模型研究的启示。
Cells. 2021 Nov 15;10(11):3175. doi: 10.3390/cells10113175.
4
A 34-Year-Old Woman with Third-Degree Heart Block and Atrial Flutter Associated with Lyme Carditis: A Case Report.一位 34 岁女性,三度房室传导阻滞和与莱姆心炎相关的房扑:病例报告。
Am J Case Rep. 2021 Oct 1;22:e933789. doi: 10.12659/AJCR.933789.
Healthcare (Basel). 2018 Sep 22;6(4):119. doi: 10.3390/healthcare6040119.
4
Leadless pacemaker used as long-term temporary therapy in Lyme carditis with high-grade atrioventricular block.无导线起搏器用于莱姆病性心肌炎伴高度房室传导阻滞的长期临时治疗。
Europace. 2019 Jan 1;21(1):8. doi: 10.1093/europace/euy175.
5
Peroperative cardiogenic shock suggesting acute coronary syndrome as initial manifestation of Lyme carditis.
J Clin Anesth. 2016 Dec;35:430-433. doi: 10.1016/j.jclinane.2016.08.005. Epub 2016 Oct 18.
6
Seasonal Activity, Density, and Collection Efficiency of the Blacklegged Tick (Ixodes scapularis) (Acari: Ixodidae) in Mid-Western Pennsylvania.宾夕法尼亚州中西部黑脚蜱(肩突硬蜱)(蜱螨亚纲:硬蜱科)的季节性活动、密度及采集效率
J Med Entomol. 2015 Nov;52(6):1260-9. doi: 10.1093/jme/tjv132. Epub 2015 Sep 3.
7
Lyme carditis--diagnosis, treatment and prognosis.莱姆病性心脏病——诊断、治疗与预后
Dtsch Arztebl Int. 2015 Mar 20;112(12):202-8. doi: 10.3238/arztebl.2015.0202.
8
Notes from the field: update on Lyme carditis, groups at high risk, and frequency of associated sudden cardiac death--United States.实地报告:美国莱姆病性心肌炎最新情况、高危人群及相关心源性猝死发生率
MMWR Morb Mortal Wkly Rep. 2014 Oct 31;63(43):982-3.
9
[Cardiac arrest due to torsades de pointes ventricular tachycardia in a patient with Lyme carditis].[莱姆病性心肌炎患者发生尖端扭转型室性心动过速所致心脏骤停]
Ugeskr Laeger. 2014 Aug 25;176(35).
10
Lyme borreliosis.莱姆病。
Lancet. 2012 Feb 4;379(9814):461-73. doi: 10.1016/S0140-6736(11)60103-7. Epub 2011 Sep 6.