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术后恶心呕吐(PONV)的预防与治疗:当前推荐及新兴疗法综述

Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies.

作者信息

Jin Zhaosheng, Gan Tong J, Bergese Sergio D

机构信息

Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA.

Department of Neurological Surgery, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA.

出版信息

Ther Clin Risk Manag. 2020 Dec 31;16:1305-1317. doi: 10.2147/TCRM.S256234. eCollection 2020.

DOI:10.2147/TCRM.S256234
PMID:33408475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7780848/
Abstract

Postoperative nausea and vomiting is one of the most frequent adverse events after surgery and anesthesia. It is distressing for the patient and can lead to other postoperative complications. Management of PONV involves a framework of risk assessment, multimodal risk reduction, and prophylactic measures, as well as prompt rescue treatment. There has been a significant paradigm shift in the approach towards PONV prevention. There have also been several emerging therapeutic options for PONV prophylaxis and treatment. In this review, we will discuss the up-to-date PONV management guidelines and highlight novel therapeutic options which have emerged in the last few years.

摘要

术后恶心呕吐是手术和麻醉后最常见的不良事件之一。它给患者带来痛苦,并可能导致其他术后并发症。术后恶心呕吐的管理涉及风险评估框架、多模式风险降低和预防措施,以及及时的抢救治疗。在预防术后恶心呕吐的方法上已经发生了重大的模式转变。在术后恶心呕吐的预防和治疗方面也出现了几种新的治疗选择。在这篇综述中,我们将讨论最新的术后恶心呕吐管理指南,并重点介绍过去几年出现的新治疗选择。

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本文引用的文献

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Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting.术后恶心呕吐管理的第四版共识指南。
Anesth Analg. 2020 Aug;131(2):411-448. doi: 10.1213/ANE.0000000000004833.
2
Successful implementation of an enhanced recovery after surgery (ERAS) protocol reduces nausea and vomiting after infratentorial craniotomy for tumour resection: a randomized controlled trial.一项增强型术后恢复(ERAS)方案在幕下肿瘤切除术患者中的成功实施可减少术后恶心和呕吐:一项随机对照试验。
BMC Neurol. 2020 Apr 22;20(1):150. doi: 10.1186/s12883-020-01699-z.
3
Palonosetron versus ondansetron for prevention of nausea and vomiting after total abdominal hysterectomy under spinal anesthesia with intrathecal morphine: a double-blind, randomized controlled trial.
Inhaling Peppermint Essential Oil as a Promising Complementary Therapy in the Treatment of Nausea and Vomiting.
吸入薄荷精油作为治疗恶心和呕吐的一种有前景的辅助疗法。
J Clin Med. 2025 Jul 17;14(14):5069. doi: 10.3390/jcm14145069.
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Indian J Anaesth. 2025 Apr;69(4):402-405. doi: 10.4103/ija.ija_1227_24. Epub 2025 Mar 13.
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Cureus. 2025 May 23;17(5):e84664. doi: 10.7759/cureus.84664. eCollection 2025 May.
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BMC Anesthesiol. 2025 Mar 20;25(1):135. doi: 10.1186/s12871-025-02987-2.
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