Vinsant Charles, Holecko Joseph, Whitson Bryan A, Turner Katja
Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Department of Cardiac Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Int J Crit Illn Inj Sci. 2020 Jul-Sep;10(3):148-151. doi: 10.4103/IJCIIS.IJCIIS_101_19. Epub 2020 Sep 22.
Mitral regurgitation (MR), one of the most common valvulopathies, occurs in at least 10% of the individuals older than 75 years. The long-standing volume overload occurring in severe MR inevitably leads to left ventricular (LV) enlargement and dysfunction; untreated, severe MR can progress to heart failure and death. Hypotension following separation from cardiopulmonary bypass after mitral valve intervention should alert an anesthesiologist to consider a myriad of differential diagnoses. This includes, but is not limited to, afterload mismatch, which can contribute to severe LV dysfunction, even in patients with seemingly normal preoperative ejection fraction. We present a case of acute on chronic biventricular failure after mitral valve repair due to afterload mismatch and discuss its management intraoperatively. Admittedly, identifying the causes of hypotension to guide treatment after mitral valve surgery in patients with severe MR is challenging. High index of suspicion and transesophageal echocardiogram guidance are important for prompt diagnosis, increasing the likelihood of successful outcomes with appropriate clinical management.
二尖瓣反流(MR)是最常见的瓣膜病之一,在至少10%的75岁以上人群中出现。严重MR中持续存在的容量超负荷不可避免地导致左心室(LV)扩大和功能障碍;未经治疗,严重MR可进展为心力衰竭和死亡。二尖瓣干预后脱离体外循环后出现的低血压应提醒麻醉医生考虑众多鉴别诊断。这包括但不限于后负荷不匹配,即使在术前射血分数看似正常的患者中,后负荷不匹配也可能导致严重的左心室功能障碍。我们报告一例因后负荷不匹配导致二尖瓣修复术后急性慢性双心室衰竭的病例,并讨论术中管理。诚然,在严重MR患者中识别二尖瓣手术后低血压的原因以指导治疗具有挑战性。高度怀疑指数和经食管超声心动图引导对于及时诊断很重要,通过适当的临床管理增加成功结果的可能性。