患有肝肿瘤犬的定量超声弹性成像与血清铁蛋白水平
Quantitative ultrasound elastography and serum ferritin level in dogs with liver tumors.
作者信息
Huaijantug Somkiat, Yatmark Paranee, Phophug Phummarin, Worapakdee Mookrawee, Phutrakul Alan, Julapanthong Pruksa, Chuaychoo Krittin
机构信息
Department of Clinical Sciences and Public Health, Faculty of Veterinary Science, Mahidol University, Nakhon Pathom, Thailand.
Department of Pre-Clinical and Apply Animal Science, Faculty of Veterinary Science, Mahidol University, Nakhon Pathom, Thailand.
出版信息
J Adv Vet Anim Res. 2020 Sep 13;7(4):575-584. doi: 10.5455/javar.2020.g455. eCollection 2020 Dec.
OBJECTIVE
The objective of this study was to assess the serum ferritin level and quantitate ultrasound elastography as a marker to distinguish dogs with benign and malignant liver tumors.
MATERIALS AND METHODS
Twenty-eight dogs were determined the serum ferritin and ultrasound elastography by using fine-needle aspiration biopsy.
RESULTS
Our results demonstrated that dogs with malignant liver tumors had significantly higher mean serum ferritin concentrations than those with benign liver tumors ( = 0.004). The mean intensity of blue and red colors from elastography was greater in the malignant than those in the benign group, especially for the blue color, meaning that lesions showed more hard tissue. Additionally, histograms of blue color in the malignant tended to be higher than the benign group.
CONCLUSION
We suggested that quantitative ultrasound elastography and serum ferritin concentration comprise an alternative and non-invasive diagnostic method that could be used to predict the type of liver tumors in dogs.
目的
本研究的目的是评估血清铁蛋白水平，并对超声弹性成像进行定量分析，以此作为区分犬良性和恶性肝肿瘤的标志物。
材料与方法
通过细针穿刺活检对28只犬测定血清铁蛋白和超声弹性成像。
结果
我们的结果表明，患有恶性肝肿瘤的犬平均血清铁蛋白浓度显著高于患有良性肝肿瘤的犬（=0.004）。弹性成像中蓝色和红色的平均强度在恶性组中比良性组更大，尤其是蓝色，这意味着病变显示出更多的硬组织。此外，恶性组蓝色的直方图往往高于良性组。
结论
我们建议，定量超声弹性成像和血清铁蛋白浓度构成一种可用于预测犬肝肿瘤类型的替代性非侵入性诊断方法。
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