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接受肝叶切除术治疗肝肿瘤的犬长期存活相关因素。

Factors associated with long-term survival in dogs undergoing liver lobectomy as treatment for liver tumors.

作者信息

Kinsey Jessica R, Gilson Stephen D, Hauptman Joe, Mehler Steve J, May Lauren R

机构信息

Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).

出版信息

Can Vet J. 2015 Jun;56(6):598-604.

Abstract

The objectives of the study were to describe clinicopathologic findings in dogs that underwent surgical treatment of liver tumors and to define outcome-associated variables in this canine population. Medical records of 118 dogs that underwent liver lobectomy were reviewed. Variables were assessed via univariate and multivariate Cox regression analyses. Hazard ratios, median survival times (MSTs), and Kaplan-Meier Survival curves (KMSCs) were created for significant variables. Of the dogs with surgically addressed hepatic tumors, 93% survived to discharge. The MST was not reached. Lethargic dogs had a mortality risk 10.2 times that of non-lethargic dogs. Non-tachypneic dogs had a mortality risk 4.3 times that of tachypneic dogs. Dogs that experienced anesthetic complications had a mortality risk 100 times that of dogs that did not. We conclude that the prognosis associated with liver tumors is good. Lethargy, respiratory rate, and anesthetic complications were associated with outcome.

摘要

本研究的目的是描述接受肝脏肿瘤手术治疗的犬只的临床病理特征,并确定该犬类群体中与预后相关的变量。回顾了118只接受肝叶切除术的犬只的病历。通过单变量和多变量Cox回归分析评估变量。为显著变量创建风险比、中位生存时间(MST)和Kaplan-Meier生存曲线(KMSC)。接受肝脏肿瘤手术治疗的犬只中,93%存活至出院。未达到中位生存时间。嗜睡的犬只死亡风险是非嗜睡犬只的10.2倍。非呼吸急促的犬只死亡风险是呼吸急促犬只的4.3倍。经历麻醉并发症的犬只死亡风险是未经历麻醉并发症犬只的100倍。我们得出结论,与肝脏肿瘤相关的预后良好。嗜睡、呼吸频率和麻醉并发症与预后相关。

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