Du Mengxi, Griecci Christina F, Kim David D, Cudhea Frederick, Ruan Mengyuan, Eom Heesun, Wong John B, Wilde Parke E, Michaud Dominique S, Lee Yujin, Micha Renata, Mozaffarian Dariush, Zhang Fang Fang
Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.
JNCI Cancer Spectr. 2020 Aug 25;4(6):pkaa073. doi: 10.1093/jncics/pkaa073. eCollection 2020 Dec.
Sugar-sweetened beverage (SSB) consumption contributes to obesity, a risk factor for 13 cancers. Although SSB taxes can reduce intake, the health and economic impact on reducing cancer burdens in the United States are unknown, especially among low-income Americans with higher SSB intake and obesity-related cancer burdens.
We used the Diet and Cancer Outcome Model, a probabilistic cohort state-transition model, to project health gains and economic benefits of a penny-per-ounce national SSB tax on reducing obesity-associated cancers among US adults aged 20 years and older by income.
A national SSB tax was estimated to prevent 22 075 (95% uncertainty interval [UI] = 16 040-28 577) new cancer cases and 13 524 (95% UI = 9841-17 681) cancer deaths among US adults over a lifetime. The policy was estimated to cost $1.70 (95% UI = $1.50-$1.95) billion for government implementation and $1.70 (95% UI = $1.48-$1.96) billion for industry compliance, while saving $2.28 (95% UI = $1.67-$2.98) billion cancer-related healthcare costs. The SSB tax was highly cost-effective from both a government affordability perspective (incremental cost-effectiveness ratio [ICER] = $1486, 95% UI = -$3516-$9265 per quality-adjusted life year [QALY]) and a societal perspective (ICER = $13 220, 95% UI = $3453-$28 120 per QALY). Approximately 4800 more cancer cases and 3100 more cancer deaths would be prevented, and $0.34 billion more healthcare cost savings would be generated among low-income (federal poverty-to-income ratio [FPIR] ≤ 1.85) than higher-income individuals (FPIR > 1.85).
A penny-per-ounce national SSB tax is cost-effective for cancer prevention in the United States, with the largest health gains and economic benefits among low-income Americans.
饮用含糖饮料(SSB)会导致肥胖,而肥胖是13种癌症的风险因素。尽管对含糖饮料征税可以减少其摄入量,但在美国,这对减轻癌症负担的健康和经济影响尚不清楚,尤其是在那些含糖饮料摄入量较高且肥胖相关癌症负担较重的低收入美国人中。
我们使用了饮食与癌症结果模型,这是一种概率队列状态转换模型,以预测每盎司征收1美分的全国性含糖饮料税对20岁及以上美国成年人中减少肥胖相关癌症的健康收益和经济效益,并按收入进行划分。
据估计,一项全国性的含糖饮料税在成年人的一生中可预防22075例(95%不确定性区间[UI]=16040 - 28577)新癌症病例和13524例(95% UI = 9841 - 17681)癌症死亡。该政策估计政府实施成本为17.0亿美元(95% UI = 15.0 - 19.5亿美元),行业合规成本为17.0亿美元(95% UI = 14.8 - 19.6亿美元),同时节省22.8亿美元(95% UI = 16.7 - 29.8亿美元)与癌症相关的医疗成本。从政府可承受性角度(增量成本效益比[ICER] = 1486美元,95% UI = - 3516 - 9265美元/质量调整生命年[QALY])和社会角度(ICER = 13220美元,95% UI = 3453 - 28120美元/QALY)来看,对含糖饮料征税具有很高的成本效益。与高收入个体(联邦贫困与收入比率[FPIR] > 1.85)相比,低收入个体(FPIR ≤ 1.85)可预防约4800例更多癌症病例和3100例更多癌症死亡,并可额外节省3.4亿美元医疗成本。
每盎司征收1美分的全国性含糖饮料税在美国预防癌症方面具有成本效益,对低收入美国人的健康收益和经济效益最大。