利用 27 个 Y-STR 对印度中部人群进行法医特征描述和遗传评估。
Forensic characterization and genetic evaluation in the Central Indian population using 27 Y-STRs.
机构信息
DNA Fingerprinting Unit, State Forensic Science Laboratory, Sagar, Madhya Pradesh, 470001, India.
DNA Division, State Forensic Science Laboratory, Jaipur, Rajasthan, 302016, India.
出版信息
Int J Legal Med. 2021 May;135(3):791-792. doi: 10.1007/s00414-020-02486-8. Epub 2021 Jan 6.
INTRODUCTION
Forensic characterization and genetic evaluation study in the 539 randomly selected unrelated adult healthy individuals belonging to the Central Indian population was undertaken.
METHODS
The study was performed using a multiplex of 27 Y-STRs incoporated in Yfiler™ Plus multiplex kit.
RESULTS
Out of 539 samples, 6 samples were observed for large deletion and tri-allelic patterns, which were removed from the analysis, and out of 533 samples, a total of 507 haplotypes were found, and out of these haplotypes, 482 unique haplotypes were found in this piece of work. The forensically important parameters, i.e., gene diversity (GD) and discrimination capacity (DC), were found to be 0.669 and 0.951, respectively, for the tested Y STR loci. The genetic data of this study will enrich the Y STR data bank and being used as a potential tool for forensic DNA and various genetic studies.
简介
对来自印度中部的 539 名随机选择的无血缘关系的成年健康个体进行法医特征描述和遗传评估研究。
方法
本研究使用了包含在 Yfiler™ Plus 多重扩增试剂盒中的 27 个 Y-STR 进行。
结果
在 539 个样本中，观察到 6 个样本存在大片段缺失和三等位基因模式，这些样本被排除在分析之外，在 533 个样本中，共发现 507 个单倍型，其中 482 个独特的单倍型在本研究中发现。测试的 Y STR 基因座的法医学重要参数，即基因多样性（GD）和鉴别能力（DC），分别为 0.669 和 0.951。本研究的遗传数据将丰富 Y STR 数据库，并作为法医 DNA 和各种遗传研究的潜在工具。
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