Department Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
Br J Neurosurg. 2023 Oct;37(5):1319-1321. doi: 10.1080/02688697.2020.1866167. Epub 2021 Jan 7.
Occlusion of foramen of Monro is an uncommon clinical entity that usually presents in children. Common causes are obstructing mass, infectious etiologies or vascular malformation. Rarely, it may be an idiopathic stricture or membrane. We report a case of idiopathic membranous obstruction of the foramen of Monro in a 45-year-old male with no past medical or surgical history. He presented with new intermittent dull and burning bifrontal severe headache for 2 d, which was alleviated slightly by non-steroidal anti-inflammatory medication. Imaging showed marked dilation of the lateral ventricles with normal third and fourth ventricles. The patient was discharged initially with conservative medical management and close follows up; however, the headache continued to progress and neurosurgical intervention was offered. The patient underwent endoscopic exploration, fenestration of the septum pellucidum, and right ventriculoperitoneal shunt placement. Bilateral membranous obstruction of foramina of Monro and an auto-fenestrated cavum septum pellucidum were identified intraoperatively. The patient reported resolution of headache post-operatively without recurrence on 1-month follow up. This case is unusual in that the patient presented without any known neurologic history or prior intracranial infections. It became apparent at the time of surgery that chronic obstruction of the bilateral foramina with collapse of the third ventricle had developed, and the safest durable treatment for him was septostomy and cerebrospinal fluid (CSF) shunt placement.
Monro 孔闭塞是一种不常见的临床实体,通常发生在儿童中。常见的原因是阻塞性肿块、感染性病因或血管畸形。很少见的情况下,它可能是特发性狭窄或隔膜。我们报告了一例特发性 Monro 孔膜性阻塞的病例,患者为 45 岁男性,无既往病史或手术史。他表现为新的间歇性钝痛和双额部严重头痛,持续 2 天,非甾体抗炎药可轻度缓解。影像学显示侧脑室明显扩张,第三和第四脑室正常。患者最初接受保守的药物治疗和密切随访,但头痛持续进展,并提供神经外科干预。患者接受了内镜探查、透明隔切开术和右脑室-腹腔分流术。术中发现双侧 Monro 孔膜性阻塞和自动开窗的透明隔腔。术后患者头痛缓解,1 个月随访时无复发。该病例不常见,患者无任何已知的神经病史或既往颅内感染。手术时发现第三脑室慢性阻塞伴塌陷,对他来说最安全持久的治疗方法是隔切开术和脑脊液(CSF)分流术。