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特发性透明隔孔膜性闭塞:成人脑积水和头痛的一种不常见病因。

Idiopathic membranous occlusion of the foramen of Monro: an unusual cause of hydrocephalus and headache in adults.

机构信息

Department Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.

出版信息

Br J Neurosurg. 2023 Oct;37(5):1319-1321. doi: 10.1080/02688697.2020.1866167. Epub 2021 Jan 7.

DOI:10.1080/02688697.2020.1866167
PMID:33410364
Abstract

Occlusion of foramen of Monro is an uncommon clinical entity that usually presents in children. Common causes are obstructing mass, infectious etiologies or vascular malformation. Rarely, it may be an idiopathic stricture or membrane. We report a case of idiopathic membranous obstruction of the foramen of Monro in a 45-year-old male with no past medical or surgical history. He presented with new intermittent dull and burning bifrontal severe headache for 2 d, which was alleviated slightly by non-steroidal anti-inflammatory medication. Imaging showed marked dilation of the lateral ventricles with normal third and fourth ventricles. The patient was discharged initially with conservative medical management and close follows up; however, the headache continued to progress and neurosurgical intervention was offered. The patient underwent endoscopic exploration, fenestration of the septum pellucidum, and right ventriculoperitoneal shunt placement. Bilateral membranous obstruction of foramina of Monro and an auto-fenestrated cavum septum pellucidum were identified intraoperatively. The patient reported resolution of headache post-operatively without recurrence on 1-month follow up. This case is unusual in that the patient presented without any known neurologic history or prior intracranial infections. It became apparent at the time of surgery that chronic obstruction of the bilateral foramina with collapse of the third ventricle had developed, and the safest durable treatment for him was septostomy and cerebrospinal fluid (CSF) shunt placement.

摘要

Monro 孔闭塞是一种不常见的临床实体,通常发生在儿童中。常见的原因是阻塞性肿块、感染性病因或血管畸形。很少见的情况下,它可能是特发性狭窄或隔膜。我们报告了一例特发性 Monro 孔膜性阻塞的病例,患者为 45 岁男性,无既往病史或手术史。他表现为新的间歇性钝痛和双额部严重头痛,持续 2 天,非甾体抗炎药可轻度缓解。影像学显示侧脑室明显扩张,第三和第四脑室正常。患者最初接受保守的药物治疗和密切随访,但头痛持续进展,并提供神经外科干预。患者接受了内镜探查、透明隔切开术和右脑室-腹腔分流术。术中发现双侧 Monro 孔膜性阻塞和自动开窗的透明隔腔。术后患者头痛缓解,1 个月随访时无复发。该病例不常见,患者无任何已知的神经病史或既往颅内感染。手术时发现第三脑室慢性阻塞伴塌陷,对他来说最安全持久的治疗方法是隔切开术和脑脊液(CSF)分流术。

相似文献

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Idiopathic membranous occlusion of the foramen of Monro: an unusual cause of hydrocephalus and headache in adults.特发性透明隔孔膜性闭塞:成人脑积水和头痛的一种不常见病因。
Br J Neurosurg. 2023 Oct;37(5):1319-1321. doi: 10.1080/02688697.2020.1866167. Epub 2021 Jan 7.
2
Neuroendoscopic treatment of idiopathic occlusion of the foramen of Monro in adults--two case reports.神经内镜治疗成人特发性孟氏孔闭塞——两例报告
Neurol Med Chir (Tokyo). 2002 Feb;42(2):81-5. doi: 10.2176/nmc.42.81.
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Endoscopic stent placement for treatment of secondary bilateral occlusion of the Monro foramina following endoscopic third ventriculostomy in a patient with aqueductal stenosis. Case report.内镜下支架置入术治疗导水管狭窄患者行内镜下第三脑室造瘘术后继发的双侧室间孔闭塞。病例报告。
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Membranous occlusion of the foramen of Monro following ventriculoperitoneal shunt insertion: a role for endoscopic foraminoplasty.脑室腹腔分流术后Monro孔的膜性闭塞:内镜下造瘘术的作用
Childs Nerv Syst. 2000 Apr;16(4):213-7. doi: 10.1007/s003810050500.
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Adult idiopatic occlusion of Monro foramina: intraoperative endoscopic reinterpretation of radiological data and review of the literature.成人特发性室间孔闭塞:术中内镜对放射学数据的重新解读及文献综述
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Bilateral occlusion of the foramina of Monro after endoscopic third ventriculostomy for aqueductal stenosis--a case report.内镜下第三脑室造瘘治疗导水管狭窄后双侧Monro孔闭塞——一例报告
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[Unilateral hydrocephalus due to membranous occlusions of the foramen of Monro (author's transl)].[由于Monro孔膜性闭塞导致的单侧脑积水(作者译)]
Acta Neurochir (Wien). 1976;33(3-4):183-212. doi: 10.1007/BF01886669.
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Neuroendoscopic Management of Coexisting Congenital Agenesis of Bilateral Foramen of Monro with Aqueductal Stenosis and Chiari Malformation: Case Report and Review of the Literature.神经内镜治疗并存的双侧室间孔先天性缺如伴导水管狭窄和Chiari畸形:病例报告及文献复习
World Neurosurg. 2018 Oct;118:55-58. doi: 10.1016/j.wneu.2018.07.016. Epub 2018 Jul 11.
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Idiopathic bilateral occlusion of the foramen of Monro: An unusual entity with varied clinical presentations.特发性双侧孟氏孔闭塞:一种临床表现多样的罕见病症。
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Isolated third and fourth ventricles associated with neurosarcoidosis successfully treated by neuroendoscopy--case report.神经内镜成功治疗与神经结节病相关的孤立性第三和第四脑室——病例报告
Neurol Med Chir (Tokyo). 2004 Aug;44(8):435-7. doi: 10.2176/nmc.44.435.

引用本文的文献

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Surgical management of biventricular hydrocephalus caused by tuberculosis-induced bilateral obstruction of the foramen of Monro: illustrative case.结核性双侧室间孔梗阻所致双脑室型脑积水的外科治疗:病例说明
J Neurosurg Case Lessons. 2025 Sep 1;10(9). doi: 10.3171/CASE25349.
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Case Report: Occlusion of the foramen of Monro treated with endoscopic septostomy and foraminotomy in a preterm neonate.病例报告:一名早产儿经内镜隔膜造口术和开孔术治疗Monro孔闭塞。
Front Surg. 2023 Dec 15;10:1257679. doi: 10.3389/fsurg.2023.1257679. eCollection 2023.
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Idiopathic bilateral occlusion of Foramen of Monro treated by septostomy with unilateral foraminoplasty: a rare case report.
经单侧造孔术行中隔造口术治疗特发性双侧孟氏孔闭塞:1例罕见病例报告
Ann Med Surg (Lond). 2023 Oct 5;85(11):5816-5819. doi: 10.1097/MS9.0000000000001391. eCollection 2023 Nov.