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神经内镜治疗成人特发性孟氏孔闭塞——两例报告

Neuroendoscopic treatment of idiopathic occlusion of the foramen of Monro in adults--two case reports.

作者信息

Freudenstein Dirk, Duffner Frank, Krapf Hilmar, Wagner Alexandra, Grote Ernst H

机构信息

Department of Neurosurgery, University Hospital-Eberhard-Karls University Tübingen, Tübingen, Germany.

出版信息

Neurol Med Chir (Tokyo). 2002 Feb;42(2):81-5. doi: 10.2176/nmc.42.81.

Abstract

Two adults presented with hydrocephalus due to idiopathic obstruction of the bilateral foramina of Monro, manifesting as clinical signs of chronically elevated intracranial pressure. No inflammation was present. The primary surgical treatment was neuroendoscopic reconstruction of the right foramen of Monro. A 37-year-old man had a spontaneous perforation of the septum pellucidum. The patient required a ventriculoperitoneal shunt, although postoperative ventriculography proved free passage of cerebrospinal fluid from the lateral ventricle into the third ventricle. A 62-year-old man underwent additional septostomy and third ventriculostomy, and the neuroendoscopic intervention relieved the presenting symptoms without additional treatment. The biopsy specimens showed no evidence of malignancy in either case. Neuroendoscopic intervention is an alternative treatment in the management of hydrocephalus due to idiopathic obstruction of the foramen of Monor. The procedure is less invasive than open microsurgical reconstruction and can even avoid ventriculoperitoneal or ventriculoatrial shunting.

摘要

两名成年人因双侧室间孔特发性梗阻出现脑积水,表现为慢性颅内压升高的临床症状。无炎症表现。主要手术治疗为神经内镜下重建右侧室间孔。一名37岁男性透明隔自发穿孔。患者需要行脑室腹腔分流术,尽管术后脑室造影显示脑脊液从侧脑室自由流入第三脑室。一名62岁男性接受了额外的造瘘术和第三脑室造瘘术,神经内镜干预缓解了当前症状,无需额外治疗。两例活检标本均未显示恶性证据。神经内镜干预是治疗因室间孔特发性梗阻导致脑积水的一种替代治疗方法。该手术比开放性显微手术重建侵入性小,甚至可以避免脑室腹腔或脑室心房分流。

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