Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.
J Bone Joint Surg Am. 2021 Mar 3;103(5):e18. doi: 10.2106/JBJS.20.01837.
Adverse local tissue reactions (ALTRs) were initially reported as complications associated with metal-on-metal (MoM) bearings; however, there is increasing concern regarding the occurrence of adverse local tissue reactions from mechanically assisted crevice corrosion (MACC) at the femoral head-neck junction or between other modular junctions of the implant containing cobalt chromium parts in patients with metal-on-polyethylene (MoP) bearings. ALTR due to MACC at the head-neck junction has primarily been reported in association with cobalt chromium alloy femoral heads. As pain following total hip arthroplasty may have various intrinsic and extrinsic causes, a systematic approach to evaluation (risk stratification algorithm) based on the currently available data is recommended to optimize patient management. Evaluation should begin by ruling out common causes of pain, including component loosening and periprosthetic joint infection. While specialized tests such as blood metal analysis and metal artifact reduction sequence magnetic resonance imaging (MARS MRI) are useful modalities in evaluating for ALTRs, over-reliance on any single investigative tool in the clinical decision-making process should be avoided. There should be a low threshold to perform a systematic evaluation for ALTR due to MACC in patients with metal-on-polyethylene total hip arthroplasty as early recognition and diagnosis is critical, as delays in appropriate treatment initiation may result in soft-tissue damage, which complicates surgical treatment and is associated with a higher risk of complications and poorer patient outcomes.
最初,不良局部组织反应 (ALTR) 被报告为与金属对金属 (MoM) 轴承相关的并发症;然而,人们越来越关注在含有钴铬部件的金属对聚乙烯 (MoP) 轴承的患者中,股骨头颈交界处或其他植入物的机械辅助缝隙腐蚀 (MACC) 引起的不良局部组织反应的发生。在与钴铬合金股骨头相关的股骨头颈交界处的 MACC 引起的 ALTR 主要被报道。由于全髋关节置换术后的疼痛可能有各种内在和外在的原因,因此建议根据现有数据采用系统的评估方法(风险分层算法)来优化患者管理。评估应从排除疼痛的常见原因开始,包括组件松动和假体周围关节感染。虽然血液金属分析和金属伪影减少序列磁共振成像 (MARS MRI) 等专门测试在评估 ALTR 方面是有用的方法,但在临床决策过程中过度依赖任何单一的检查工具都应避免。对于金属对聚乙烯全髋关节置换术后因 MACC 引起的 ALTR,应进行系统评估,因为早期识别和诊断至关重要,因为延迟适当的治疗开始可能导致软组织损伤,这会使手术治疗复杂化,并与更高的并发症风险和更差的患者预后相关。