Department of Child and Adolescent Psychiatry, Medical University of Warsaw, Warsaw, Poland.
Institute of Human Biology and Evolution, Faculty of Biology Adam Mickiewicz University, Poznan, Poland.
J Child Adolesc Psychopharmacol. 2021 Aug;31(6):430-438. doi: 10.1089/cap.2020.0075. Epub 2021 Jan 7.
This study aimed to assess the prevalence of overweight and obesity in the group of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) according to three different diagnostic criteria for obesity. The effect of ADHD treatment on the risk of obesity was controlled. The study group consisted of 58 subjects aged from 8 to 17 years with ADHD. Control group consisted of 62 healthy age- and sex-matched children and adolescents. Overweight and obesity were assessed according to International Obesity Task-Force (IOTF), World Health Organization (WHO) and European Childhood Obesity Group (ECOG) criteria. There was a significantly higher incidence of obesity in ADHD group according to WHO (ADHD vs. Control: 17.2% vs. 3.2%, = 0.01) and IOTF criteria (ADHD vs. Control: 10.3% vs. 1.6%, = 0.04), but no significant difference according to ECOG criteria. There was significantly higher occurrence of overweight (20.7% vs. 12.8%, < 0.001), obesity (10.3% vs. 3.5%, < 0.001), and overweight and obesity (31.0% vs. 16.3%, < 0.001) in the ADHD group compared to the Polish population. The analysis did not show a statistically significant relationship between the amount of taken psychostimulant and the occurrence of overweight and obesity. The prevalence of overweight and obesity in the group of ADHD children and adolescents varies depending on the choice of diagnostic criteria. At the same time, it is significantly more frequent than in the general population. We suggest that future studies should give a clear rationale for the selection of cutoff points to minimize errors that could confound data analysis and interpretation.
本研究旨在评估三种不同肥胖诊断标准下患有注意力缺陷多动障碍(ADHD)的儿童和青少年超重和肥胖的流行率。同时控制 ADHD 治疗对肥胖风险的影响。研究组由 58 名 8 至 17 岁的 ADHD 患者组成。对照组由 62 名年龄和性别匹配的健康儿童和青少年组成。超重和肥胖按照国际肥胖工作组(IOTF)、世界卫生组织(WHO)和欧洲儿童肥胖组(ECOG)标准进行评估。根据 WHO(ADHD 与对照组:17.2%与 3.2%, = 0.01)和 IOTF 标准(ADHD 与对照组:10.3%与 1.6%, = 0.04),ADHD 组肥胖的发生率显著更高,但根据 ECOG 标准,差异无统计学意义。与波兰人群相比,ADHD 组超重(20.7%与 12.8%, < 0.001)、肥胖(10.3%与 3.5%, < 0.001)和超重肥胖(31.0%与 16.3%, < 0.001)的发生率显著更高。分析未显示服用的精神兴奋剂量与超重和肥胖的发生之间存在统计学上的显著关系。ADHD 儿童和青少年超重和肥胖的流行率取决于诊断标准的选择。同时,它明显比一般人群更为常见。我们建议未来的研究应明确选择切点的理由,以最大程度地减少可能混淆数据分析和解释的错误。