Respiratory Disease Center, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan.
BMC Infect Dis. 2021 Jan 7;21(1):32. doi: 10.1186/s12879-020-05715-y.
Legionnaire's disease is one of the major causes of community-acquired pneumonia and is occasionally complicated by neurological symptoms. However, reports of ocular lesions due to Legionnaire's disease are limited.
We report the case of a patient with Legionnaire's disease presenting as bilateral central scotomata due to retinal lesions. The patient consulted due to fever and bilateral central scotomata, as well as other extrapulmonary symptoms. Optical coherence tomography (OCT) showed bilateral accumulations of fluid under the retina, and the patient was diagnosed with bilateral exudative retinal detachment. Later, Legionnaire's disease was confirmed by pulmonary infiltrates on chest imaging and positive urinary antigen for Legionella pneumophila. After administration of antibiotics, the bilateral central scotomata and bilateral subretinal fluid accumulations completely resolved, as did the other extrapulmonary symptoms and the pulmonary infiltrates. Thus, the bilateral central scotomata due to exudative retinal detachment were thought to be caused by Legionnaire's disease.
This case demonstrates that Legionnaire's disease can present as bilateral central scotomata. We may consider the possibility of extrapulmonary involvement complicating Legionnaire's disease when we encounter bilateral ocular lesions in patients with fever and pneumonia.
军团病是社区获得性肺炎的主要病因之一,偶尔伴有神经系统症状。然而,军团病引起眼部病变的报道较少。
我们报告了一例因视网膜病变而出现双侧中心性暗点的军团病患者。患者因发热和双侧中心性暗点以及其他肺外症状就诊。光学相干断层扫描(OCT)显示双侧视网膜下积液积聚,患者被诊断为双侧渗出性视网膜脱离。随后,通过胸部影像学显示肺部浸润和尿肺炎军团菌抗原阳性证实了军团病的诊断。抗生素治疗后,双侧中心性暗点和双侧视网膜下积液完全消退,其他肺外症状和肺部浸润也消退。因此,认为渗出性视网膜脱离引起的双侧中心性暗点是由军团病引起的。
本病例表明军团病可表现为双侧中心性暗点。当我们遇到发热和肺炎的患者出现双侧眼部病变时,我们可能会考虑军团病并发肺外受累的可能性。