腕踝针疗法对癌痛有积极影响：一项荟萃分析。
Wrist-ankle acupuncture has a positive effect on cancer pain: a meta-analysis.
机构信息
Oncology Department of the First Affiliated Hospital of Soochow University, No. 188 Shizi Road, Suzhou, 215006, China.
School of Nursing, Medical College of Soochow University, No. 188 Shizi Road, Suzhou, 215006, China.
出版信息
BMC Complement Med Ther. 2021 Jan 7;21(1):24. doi: 10.1186/s12906-020-03193-y.
BACKGROUND
Wrist-ankle acupuncture (WAA) as a kind of micro acupuncture therapy has been used to management cancer pain, however, the effects of WAA on cancer pain were controversial in the current studies. Therefore, the purpose of this meta-analysis was to critically evaluate the effect of wrist-ankle acupuncture (WAA) on cancer pain.
METHODS
Seven digital databases were searched from the inception of databases to July 2020, including CNKI, Wanfang, VIP, CBM, Cochrane Library, PubMed and Embase. Randomized controlled trials conforming to the inclusion and exclusion criteria were screened and extracted; the risk of bias was evaluated using the Cochrane Collaboration criteria. The primary outcome indicators included pain relief rate and pain score, and the secondary outcome was adverse reaction incidence. All analyses were performed with Review Manager 5.3.
RESULTS
A total of 13 studies with 1005 cancer patients (intervention group: 568, control group: 437) were included in this meta-analysis. The results demonstrated that the pain relief rate of experimental group (WAA / WAA + drug intervention) was better than that of control group (analgesic drug intervention), and the difference was statistically significant [RR = 1.31, 95%CI: 1.15 ~ 1.49, P < 0.01].
CONCLUSIONS
WAA has certain effect on cancer pain, and the effect of WAA combined with pharmacological intervention is better than that of drug therapy alone.
背景
腕踝针（WAA）作为一种微针疗法，已被用于治疗癌症疼痛，但目前的研究对 WAA 治疗癌症疼痛的效果存在争议。因此，本荟萃分析的目的是批判性地评估腕踝针（WAA）治疗癌症疼痛的效果。
方法
从数据库建立到 2020 年 7 月，检索了 7 个数字数据库，包括中国知网、万方、维普、中国生物医学文献服务系统、Cochrane 图书馆、PubMed 和 Embase。筛选出符合纳入和排除标准的随机对照试验，并提取数据；使用 Cochrane 协作偏倚风险评估工具评估偏倚风险。主要结局指标包括疼痛缓解率和疼痛评分，次要结局指标为不良反应发生率。所有分析均使用 Review Manager 5.3 进行。
结果
共纳入 13 项研究，共 1005 例癌症患者（实验组：568 例，对照组：437 例）。结果表明，实验组（WAA/WAA+药物干预）的疼痛缓解率优于对照组（药物干预），差异具有统计学意义[RR=1.31, 95%CI: 1.15~1.49, P<0.01]。
结论
WAA 对癌症疼痛有一定疗效，WAA 联合药物干预的效果优于单纯药物治疗。
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