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日本第三方支付视角下的严重创伤混合急诊室系统的成本效益:一项卫生技术评估。

Cost-effectiveness of a hybrid emergency room system for severe trauma: a health technology assessment from the perspective of the third-party payer in Japan.

机构信息

Division of Trauma and Surgical Critical Care, Osaka General Medical Center, 3-1-56 Bandai-Higashi, Sumiyoshi-ku, Osaka, 558-8558, Japan.

Master of Public Health Program, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

出版信息

World J Emerg Surg. 2021 Jan 7;16(1):2. doi: 10.1186/s13017-020-00344-x.

Abstract

BACKGROUND

Hybrid emergency room (ER) systems, consisting of an angiography-computed tomography (CT) machine in a trauma resuscitation room, are reported to be effective for reducing death from exsanguination in trauma patients. We aimed to investigate the cost-effectiveness of a hybrid ER system in severe trauma patients without severe traumatic brain injury (TBI).

METHODS

We conducted a cost-utility analysis comparing the hybrid ER system to the conventional ER system from the perspective of the third-party healthcare payer in Japan. A short-term decision tree and a long-term Markov model using a lifetime time horizon were constructed to estimate quality-adjusted life years (QALYs) and associated lifetime healthcare costs. Short-term mortality and healthcare costs were derived from medical records and claims data in a tertiary care hospital with a hybrid ER. Long-term mortality and utilities were extrapolated from the literature. The willingness-to-pay threshold was set at $47,619 per QALY gained and the discount rate was 2%. Deterministic and probabilistic sensitivity analyses were conducted.

RESULTS

The hybrid ER system was associated with a gain of 1.03 QALYs and an increment of $33,591 lifetime costs compared to the conventional ER system, resulting in an ICER of $32,522 per QALY gained. The ICER was lower than the willingness-to-pay threshold if the odds ratio of 28-day mortality was < 0.66. Probabilistic sensitivity analysis indicated that the hybrid ER system was cost-effective with a 79.3% probability.

CONCLUSION

The present study suggested that the hybrid ER system is a likely cost-effective strategy for treating severe trauma patients without severe TBI.

摘要

背景

杂交急诊室(ER)系统,由创伤复苏室中的血管造影计算机断层扫描(CT)机组成,据报道可有效降低创伤患者出血性休克死亡的风险。我们旨在研究在没有严重创伤性脑损伤(TBI)的严重创伤患者中,杂交 ER 系统的成本效益。

方法

我们从日本第三方医疗保健支付者的角度,进行了一项成本效用分析,比较了杂交 ER 系统与常规 ER 系统。构建了一个短期决策树和一个长期 Markov 模型,使用终生时间范围来估计质量调整生命年(QALYs)和相关终生医疗保健成本。短期死亡率和医疗保健成本源自一家拥有杂交 ER 的三级护理医院的病历和索赔数据。长期死亡率和效用值从文献中推断得出。支付意愿阈值设定为每获得一个 QALY 支付 47,619 美元,贴现率为 2%。进行了确定性和概率敏感性分析。

结果

与常规 ER 系统相比,杂交 ER 系统可获得 1.03 个 QALYs 的增益和 33,591 美元的终生成本增量,导致每获得一个 QALY 的增量成本为 32,522 美元。如果 28 天死亡率的优势比<0.66,那么 ICER 低于支付意愿阈值。概率敏感性分析表明,杂交 ER 系统具有 79.3%的可能性是具有成本效益的。

结论

本研究表明,杂交 ER 系统可能是治疗没有严重 TBI 的严重创伤患者的一种具有成本效益的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cc4/7791815/6456cd2b6e2b/13017_2020_344_Fig1_HTML.jpg

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