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胺硼烷络合物引发的SFCl自由基对烯烃和炔烃的加成反应。

Amine-borane complex-initiated SFCl radical addition on alkenes and alkynes.

作者信息

Gilbert Audrey, Langowski Pauline, Delgado Marine, Chabaud Laurent, Pucheault Mathieu, Paquin Jean-François

机构信息

Départment de chimie, Université Laval, Québec, QC, G1V 0A6, Canada.

Institut des Sciences Moléculaires - Groupe ORGA - UMR 5255, Université de Bordeaux, 351 Cours de la libération, 33405 Talence, France.

出版信息

Beilstein J Org Chem. 2020 Dec 16;16:3069-3077. doi: 10.3762/bjoc.16.256. eCollection 2020.

DOI:10.3762/bjoc.16.256
PMID:33414854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7753108/
Abstract

The SFCl radical addition on unsaturated compounds was performed using an air-stable amine-borane complex as the radical initiator. This method showed to be complementary to the classic EtB-mediated SFCl addition on alkenes and alkynes. A total of seven alkene and three alkyne derivatives were tested in the reaction, with yields ranging from 3% to 85%.

摘要

使用空气稳定的胺硼烷络合物作为自由基引发剂，进行了SFCl自由基对不饱和化合物的加成反应。该方法被证明是对经典的EtB介导的SFCl对烯烃和炔烃加成反应的补充。总共七种烯烃和三种炔烃衍生物在该反应中进行了测试，产率范围为3%至85%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/2d4852000c84/Beilstein_J_Org_Chem-16-3069-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/6d185e7ab065/Beilstein_J_Org_Chem-16-3069-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/d9f3f1033e71/Beilstein_J_Org_Chem-16-3069-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/71e9be5221a4/Beilstein_J_Org_Chem-16-3069-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/80de40a0a240/Beilstein_J_Org_Chem-16-3069-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/2d4852000c84/Beilstein_J_Org_Chem-16-3069-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/6d185e7ab065/Beilstein_J_Org_Chem-16-3069-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/d9f3f1033e71/Beilstein_J_Org_Chem-16-3069-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/71e9be5221a4/Beilstein_J_Org_Chem-16-3069-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/80de40a0a240/Beilstein_J_Org_Chem-16-3069-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cc/7753108/2d4852000c84/Beilstein_J_Org_Chem-16-3069-g006.jpg

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