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Pilot study of reloxaliase in patients with severe enteric hyperoxaluria and hyperoxalemia.

作者信息

Pfau Anja, Grujic Danica, Keddis Mira T, Kausz Annamaria T, Lieske John C, Knauf Felix

机构信息

Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany.

Allena Pharmaceuticals, Inc., Newton, MA, USA.

出版信息

Nephrol Dial Transplant. 2021 Apr 26;36(5):945-948. doi: 10.1093/ndt/gfaa379.

DOI:10.1093/ndt/gfaa379
PMID:33416876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8075375/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35a1/8075375/43e3989b6328/gfaa379f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35a1/8075375/43e3989b6328/gfaa379f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35a1/8075375/43e3989b6328/gfaa379f1.jpg

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2
End Points for Clinical Trials in Primary Hyperoxaluria.原发性高草酸尿症临床试验的终点。
Clin J Am Soc Nephrol. 2020 Jul 1;15(7):1056-1065. doi: 10.2215/CJN.13821119. Epub 2020 Mar 12.
3
The association of calcium oxalate deposition in kidney allografts with graft and patient survival.肾移植中草酸钙沉积与移植物和患者存活率的关系。
Adv Kidney Dis Health. 2023 Mar;30(2):164-176. doi: 10.1053/j.akdh.2022.12.004.
4
Oxalate homeostasis.草酸盐稳态。
Nat Rev Nephrol. 2023 Feb;19(2):123-138. doi: 10.1038/s41581-022-00643-3. Epub 2022 Nov 3.
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Oxalate nephropathy: a review.草酸盐肾病:综述
Clin Kidney J. 2021 Aug 12;15(2):194-204. doi: 10.1093/ckj/sfab145. eCollection 2022 Feb.
Nephrol Dial Transplant. 2020 May 1;35(5):888-894. doi: 10.1093/ndt/gfy271.
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Transplant Direct. 2017 Nov 8;3(12):e331. doi: 10.1097/TXD.0000000000000748. eCollection 2017 Dec.
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Plasma oxalate in relation to eGFR in patients with primary hyperoxaluria, enteric hyperoxaluria and urinary stone disease.原发性高草酸尿症、肠道高草酸尿症和尿路结石病患者的血浆草酸盐与估算肾小球滤过率的关系
Clin Biochem. 2017 Dec;50(18):1014-1019. doi: 10.1016/j.clinbiochem.2017.07.017. Epub 2017 Jul 29.
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A Double-Blind, Placebo Controlled, Randomized Phase 1 Cross-Over Study with ALLN-177, an Orally Administered Oxalate Degrading Enzyme.一项关于口服草酸盐降解酶ALLN-177的双盲、安慰剂对照、随机1期交叉研究。
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