Brandman Onn, Frost Adam
Department of Biochemistry, Stanford University, Palo Alto, CA 94305, USA.
Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Mol Cell. 2021 Jan 7;81(1):6-7. doi: 10.1016/j.molcel.2020.12.032.
C-terminal tailing is an ancient and conserved form of peptide synthesis that protects cells from incomplete and potentially toxic translation products. Filbeck et al. (2020) and Crowe-McAuliffe et al. (2020) use structural, genetic, and biochemical approaches to elucidate the mechanisms driving C-terminal tailing.
C末端加尾是一种古老且保守的肽合成形式，可保护细胞免受不完整且可能有毒的翻译产物的影响。菲尔贝克等人（2020年）和克罗-麦考利夫等人（2020年）使用结构、遗传和生化方法来阐明驱动C末端加尾的机制。
