Miller B M, Kozarek R A, Ryan J A, Ball T J, Traverso L W
Department of Surgery, Virginia Mason Medical Center, Seattle, Washington.
Ann Surg. 1988 Feb;207(2):135-41. doi: 10.1097/00000658-198802000-00004.
The charts of all patients with common bile duct (CBD) stones admitted to Virginia Mason Medical Center between January 1, 1981 and July 31, 1986 were reviewed to define current methods of management and results of operative versus endoscopic therapy. Two hundred thirty-seven patients with CBD stones were treated. One hundred thirty patients had intact gallbladders. Of these patients, 76 (59%) underwent cholecystectomy and common bile duct exploration (CBDE) while 54 (41%) underwent endoscopic papillotomy (EP) only. Of the 107 patients admitted with recurrent stones after cholecystectomy, all but five were treated with EP. The overall mortality rate was 3.0%. Complications, success, and death rates were all similar for CBDE and EP, but the complications of EP were often serious and directly related to the procedure (GI hemorrhage, 6; duodenal perforation, 5; biliary sepsis, 4; pancreatitis, 1). Patients undergoing EP required significantly shorter hospitalization than those undergoing CBDE. Multivariate analysis showed that age greater than 70 years, technical failure, and complications increased the risk of death, regardless of procedure performed. Twenty-one per cent of those undergoing EP with gallbladders intact eventually required cholecystectomy. The conclusion is that the results of EP and CBDE are similar, and the use of EP has not reduced the mortality rates of this disease.
回顾了1981年1月1日至1986年7月31日期间入住弗吉尼亚梅森医疗中心的所有胆总管结石患者的病历,以确定当前的治疗方法以及手术治疗与内镜治疗的结果。共有237例胆总管结石患者接受了治疗。其中130例患者胆囊完整。在这些患者中,76例(59%)接受了胆囊切除术和胆总管探查术(CBDE),而54例(41%)仅接受了内镜乳头切开术(EP)。在107例胆囊切除术后复发结石的患者中,除5例之外均接受了EP治疗。总体死亡率为3.0%。CBDE和EP的并发症、成功率及死亡率均相似,但EP的并发症往往较为严重且与手术直接相关(消化道出血6例;十二指肠穿孔5例;胆源性败血症4例;胰腺炎1例)。接受EP治疗的患者住院时间明显短于接受CBDE治疗的患者。多因素分析表明,年龄大于70岁、技术失败及并发症会增加死亡风险,与所施行的手术方式无关。胆囊完整且接受EP治疗的患者中,21%最终需要接受胆囊切除术。结论是,EP和CBDE的结果相似,且EP的应用并未降低该病的死亡率。