Granke K, Jordan F T, Mazzeo R J, Strasius S R
Department of General Surgery, St. Joseph Mercy Hospital, Ann Arbor, Michigan 48106.
Am Surg. 1988 Jun;54(6):347-51.
High mortality rates reported with common bile duct exploration (CBDE), 3.4 per cent to as high as 30 per cent in re-exploration of those over 70 years of age, prompted review of endoscopic papillotomy (EP) for stone extraction in a community hospital as well as an attempt to assess its impact on the treatment of common duct stones. Endoscopic papillotomy in 237 patients had a 1.3 per cent mortality. Successful extraction of the stone occurred in 91.6 per cent of 108 patients followed for at least 2 years with no further treatment required. Morbidity and mortality was uneffected by previous biliary surgery, repeat attempts at stone extraction or EP performed prior to cholecystectomy (P greater than 0.1). The results of treatment for choledocholithiasis in 111 consecutive patients was then retrospectively reviewed to assess the impact of endoscopic papillotomy. CBDE was used initially in 79 and EP in 32 patients. Previous cholecystectomy and age biased the selection for endoscopic papillotomy (P less than 0.01). The mean ages were 57.8 years and 70.6 years (P less than 0.01), for CBDE and EP pts respectively. Age adjusted hospital stay was significantly longer for common bile duct exploration (P = 0.002). Overall, morbidity was not different between the treatment modalities (P = 0.50) and each group had one death (P = 0.23). In this community hospital, endoscopic papillotomy is safe, effective, and was reserved mainly for older patients or those with prior cholecystectomy and choledocholithiasis.(ABSTRACT TRUNCATED AT 250 WORDS)
据报道,胆总管探查术(CBDE)的死亡率较高,在70岁以上患者的再次探查中,死亡率为3.4%至高达30%,这促使一家社区医院对内镜乳头切开术(EP)取石进行评估,并试图评估其对胆总管结石治疗的影响。237例行内镜乳头切开术患者的死亡率为1.3%。108例至少随访2年且无需进一步治疗的患者中,结石成功取出率为91.6%。既往胆道手术、多次取石尝试或胆囊切除术前行内镜乳头切开术对发病率和死亡率无影响(P>0.1)。然后回顾性分析111例连续胆总管结石患者的治疗结果,以评估内镜乳头切开术的影响。最初79例患者采用胆总管探查术,32例患者采用内镜乳头切开术。既往胆囊切除术和年龄影响内镜乳头切开术的选择(P<0.01)。胆总管探查术和内镜乳头切开术患者的平均年龄分别为57.8岁和70.6岁(P<0.01)。胆总管探查术的年龄校正住院时间明显更长(P=0.002)。总体而言,两种治疗方式的发病率无差异(P=0.50),每组各有1例死亡(P=0.23)。在这家社区医院,内镜乳头切开术安全、有效,主要用于老年患者或既往有胆囊切除术和胆总管结石的患者。(摘要截短至250字)