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一项对家庭室内氡测量进行的 10 年随访研究,对其他研究的回顾以及对肺癌风险估计的影响。

A 10-year follow-up study of yearly indoor radon measurements in homes, review of other studies and implications on lung cancer risk estimates.

机构信息

Istituto Superiore di Sanità (Italian National Institute of Health), National Center for Radiation Protection and Computational Physics, v.le Regina Elena, 266 - 00161 Rome, Italy.

Istituto Superiore di Sanità (Italian National Institute of Health), National Center for Radiation Protection and Computational Physics, v.le Regina Elena, 266 - 00161 Rome, Italy.

出版信息

Sci Total Environ. 2021 Mar 25;762:144150. doi: 10.1016/j.scitotenv.2020.144150. Epub 2020 Dec 9.

DOI:10.1016/j.scitotenv.2020.144150
PMID:33418274
Abstract

Uncertainty on long-term average radon concentration has a large impact on lung cancer risk assessment in epidemiological studies. The uncertainty can be estimated by year-to-year radon concentration variability, however few data are available. In Italy a study has been planned and conducted to evaluate year-to-year radon variability over several years in normally inhabited dwellings, mainly located in Rome. This is the longest study of this kind in Europe; repeat radon measurements are carried out for 10 years using LR-115 radon detectors in the same home in consecutive years. The study includes 84 dwellings with long-term average radon concentration ranging from 28 to 636 Bq/m. The result shows that year-to-year variability of repeated measurements made in the same home in different years is low, with an overall coefficient of variation of 17%. This is smaller than most of those observed in studies from other European countries and USA, ranging from 15% to 62%. Influencing factors that may explain the differences between this study and other studies have been discussed. Due to the low yearly variability estimated in the present 10-year study, a negligible impact on lung cancer risk estimate for the Italian epidemiological study is expected.

摘要

长期平均氡浓度的不确定性对流行病学研究中的肺癌风险评估有很大影响。这种不确定性可以通过氡浓度的年际变化来估计,但是可用的数据很少。在意大利,已经计划并开展了一项研究,以评估多年来正常居住的房屋中的氡年际变化,这些房屋主要位于罗马。这是欧洲此类研究中持续时间最长的研究;使用 LR-115 氡探测器在同一房屋中连续多年进行重复测量,进行了长达 10 年的测量。该研究包括 84 个氡浓度长期平均值从 28 到 636 Bq/m 的住宅。结果表明,在不同年份在同一房屋中进行的重复测量的年际变化较小,总体变异系数为 17%。这比大多数来自其他欧洲国家和美国的研究中观察到的结果小,范围在 15%到 62%之间。讨论了可能解释本研究与其他研究之间差异的影响因素。由于在目前的 10 年研究中估计的年变化率较低,预计对意大利流行病学研究中的肺癌风险估计的影响可以忽略不计。

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