Siegman-Igra Y, Schwartz D, Konforti N, Perluk C, Rozin R R
Infectious Disease Unit, Rokach Hospital, Tel Aviv (Israel) Medical Center.
Arch Surg. 1988 Mar;123(3):366-8. doi: 10.1001/archsurg.1988.01400270106016.
One hundred four strains of microorganisms were isolated from the blood in 76 episodes of septicemia originating from biliary tract infection. The 70 patients involved included 40 with acute cholecystitis without previous surgery, 17 with cholangitis following previous surgery, and 13 patients with malignant disease, with or without previous surgery. The most common organisms were Escherichia coli, Klebsiella, Streptococcus, and Proteus. Various streptococci, most of them from group D, were involved in 21% of the episodes. Twenty-five patients underwent surgery following the bacteremia. In ten of 12 operations performed shortly after the septicemia, bile culture yielded the same organism(s) as in the blood. The types of organisms in blood, and especially the important role of streptococci, must be taken into consideration when choosing antibiotics for therapy for and prevention of biliary septicemia.
从76例源于胆道感染的败血症患者血液中分离出104株微生物。涉及的70例患者包括40例既往未手术的急性胆囊炎患者、17例既往手术后发生胆管炎的患者以及13例有或无既往手术史的恶性疾病患者。最常见的微生物是大肠杆菌、克雷伯菌、链球菌和变形杆菌。各种链球菌,其中大多数来自D组,在21%的病例中出现。25例患者在菌血症后接受了手术。在败血症后不久进行的12例手术中的10例中,胆汁培养结果与血液中发现的微生物相同。在选择治疗和预防胆源性败血症的抗生素时,必须考虑血液中的微生物类型,尤其是链球菌的重要作用。