Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea.
Department of Pathology, Ajou University School of Medicine, Suwon, Republic of Korea.
Anticancer Res. 2021 Jan;41(1):459-466. doi: 10.21873/anticanres.14796.
BACKGROUND/AIM: Currently, there are no standard guidelines for the waiting time from the diagnosis of gastric neoplasms to endoscopic submucosal dissection (ESD).
A total of 1,605 patients who had undergone ESD for early gastric cancer (EGC) or high-grade dysplasia (HGD) were enrolled. Waiting time for ESD was defined as the time from the first diagnosis to ESD. Multivariable logistic regression analysis was conducted.
The curative resection rate was 86.8% and the mean waiting time was 36.8 days. In the multivariable model, longer waiting time did not significantly affect non-curative resection, whereas age >70 years, submucosal fibrosis, and initial cancer diagnosis were significantly associated with non-curative resection. Waiting time was still not identified as a risk factor for non-curative resection in EGC and HGD groups.
A longer waiting time from diagnosis to ESD was not associated with non-curative resection.
背景/目的：目前，对于从胃肿瘤诊断到内镜黏膜下剥离术（ESD）的等待时间，尚无标准指南。
共纳入 1605 名接受内镜黏膜下剥离术（ESD）治疗早期胃癌（EGC）或高级别上皮内瘤变（HGD）的患者。ESD 的等待时间定义为从首次诊断到 ESD 的时间。进行了多变量逻辑回归分析。
完全切除率为 86.8%，平均等待时间为 36.8 天。在多变量模型中，较长的等待时间并不会显著影响非治愈性切除，而年龄＞70 岁、黏膜下纤维化和初始癌症诊断与非治愈性切除显著相关。等待时间在 EGC 和 HGD 组中也未被确定为非治愈性切除的危险因素。
从诊断到 ESD 的较长等待时间与非治愈性切除无关。
