Case Western Reserve University School of Medicine, Cleveland, OH, USA.
University Hospitals Cleveland Medical Center, Urology Institute, Mailstop LKS 5046, 11100 Euclid Ave, Cleveland, OH, 44106, USA.
Curr Urol Rep. 2021 Jan 9;22(2):11. doi: 10.1007/s11934-020-01023-9.
To highlight and review encouraging preliminary studies behind several alternative products and interventions for erectile dysfunction (ED).
Alternative treatments for ED are becoming more prevalent with increased consumer interest. "Natural" products are sold online, and numerous clinics offer various off-label and investigational interventions. These alternative treatments have demonstrated varying degrees of efficacy in randomized trials and meta-analyses, but none of these interventions has robust enough evidence to be considered first-line therapy. These treatments may find a role in combination with guideline treatments or may be used in novel penile rehabilitation research protocols. With growing interest in alternative treatment for men's health, an awareness of the literature is imperative for patient counsel. Alternative treatments, like L-arginine, have a growing body of evidence for efficacy in combination with PDE5i, and low-intensity shock wave therapy and stem cell therapy continue to demonstrate encouraging outcomes in ED trials.
强调并回顾几种用于治疗勃起功能障碍（ED）的替代产品和干预措施背后令人鼓舞的初步研究。
随着消费者兴趣的增加，ED 的替代治疗方法越来越流行。“天然”产品在网上销售，许多诊所提供各种非标签和研究性干预措施。这些替代治疗方法在随机试验和荟萃分析中显示出不同程度的疗效，但这些干预措施都没有足够有力的证据被认为是一线治疗方法。这些治疗方法可能在与指南治疗相结合时发挥作用，或者可能用于新的阴茎康复研究方案中。随着人们对男性健康替代治疗的兴趣日益浓厚，了解相关文献对于患者咨询至关重要。替代治疗方法，如精氨酸，与 PDE5i 联合使用的疗效证据不断增加，低强度冲击波治疗和干细胞治疗在 ED 试验中继续显示出令人鼓舞的结果。
