Al-Shawaf T, Akiel A, Moghraby S A
Department of Obstetrics and Gynaecology, Medical College, King Saud University, Riyadh, Saudi Arabia.
Br J Obstet Gynaecol. 1988 Jan;95(1):84-90. doi: 10.1111/j.1471-0528.1988.tb06485.x.
A total of 1088 pregnant women was screened for abnormalities in glucose metabolism at the initial antenatal visit; those with specific risk factors were screened again after 28 weeks gestation. In 210 (19.3%) plasma glucose measured 2 h after a 75 g glucose load was greater than or equal to 7.8 mmol/l (140 mg/dl). Follow-up glucose tolerance tests revealed an overall prevalence of abnormal tests of 10.3% (112 of 1088) according to the WHO criteria, of which 21 (1.9%) were diagnosed as gestational diabetes, and 91 (8.4%) as impaired glucose tolerance. This high prevalence was significantly related to age, parity and body mass index. Screening and diagnosis using criteria set by the WHO were found acceptable and are recommended to help resolve the international disagreement on diagnostic criteria of glucose metabolism abnormalities in pregnancy.
共有1088名孕妇在首次产前检查时接受了葡萄糖代谢异常筛查；有特定危险因素的孕妇在妊娠28周后再次接受筛查。在1088名孕妇中，210名（19.3%）在口服75克葡萄糖后2小时测得的血糖大于或等于7.8毫摩尔/升（140毫克/分升）。根据世界卫生组织标准进行的后续葡萄糖耐量试验显示，异常试验的总体患病率为10.3%（1088例中的112例），其中21例（1.9%）被诊断为妊娠期糖尿病，91例（8.4%）为糖耐量受损。这种高患病率与年龄、产次和体重指数显著相关。使用世界卫生组织制定的标准进行筛查和诊断被认为是可以接受的，建议采用这些标准来解决国际上关于妊娠葡萄糖代谢异常诊断标准的分歧。
