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哈萨克斯坦假丝酵母:一次出人意料的人类胸腔积液样本之旅。

Kazachstania slooffiae: An unexpected journey to a human pleural sample.

机构信息

MIVEGEC, University Montpellier, CHU de Nîmes, CNRS, IRD, Montpellier, France.

Institut Pasteur, CNRS, Molecular Mycology Unit, National Reference Center for Invasive Mycoses & Antifungals, UMR 2000, Paris, France.

出版信息

J Mycol Med. 2021 Jun;31(2):101109. doi: 10.1016/j.mycmed.2020.101109. Epub 2020 Dec 30.

Abstract

We report a case of a 50-year-old shepherd hospitalized in intensive care unit for hiatal hernia complicated by an occlusive syndrome. In post-surgery, an acute respiratory distress occurs due to mediastinitis with large pleural effusion. At the laboratory, direct examination of the pleural sample revealed the presence of pseudohyphae. Kazachstania slooffiae was identified by Mass Spectrometry and confirmed by DNA sequencing. This uncommon yeast has never been previously described in human infections. Although its pathogenicity is not well known, K. slooffiae should be considered in the case of critically ill patients.

摘要

我们报告了一例 50 岁牧羊人因食管裂孔疝并发阻塞综合征而住院的病例。手术后,由于纵隔炎合并大量胸腔积液,出现急性呼吸窘迫。实验室检查发现胸腔积液样本直接镜检可见假菌丝。通过质谱和 DNA 测序鉴定为斯洛夫拟内孢霉。这种不常见的酵母在人类感染中从未被描述过。尽管其致病性尚不清楚,但在危重病患者中应考虑到 K. slooffiae 的存在。

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