Boissin-Agasse L, Alonso G, Roch G, Boissin J
Laboratoire de Neurobiologie Endocrinologique, (UA 1197) CNRS, Université de Montpellier-II, France.
Cell Tissue Res. 1988 Jan;251(1):153-9. doi: 10.1007/BF00215460.
The hypothalamic systems secreting corticotropin-releasing hormone (CRF), somatostatin, oxytocin, vasopressin and luteinizing hormone-releasing hormone (LHRH) were characterized using immunochemistry, and variations were studied in relation to the recrudescence of testicular activity in the ferret and the mink, two species with opposite photoregulation of their annual reproductive cycles. Under the present conditions of study, the immunoreactivity of the CRF, somatostatin, and oxytocin systems showed no significant variation in either species. In contrast, in these two species, the immunoreactivity of the LHRH system varied considerably depending on the date of observation. The increase in the number and immunoreactivity of the LHRH-secreting neurons that occurred in November in the mink and in January in the ferret, is in agreement with previous results showing that the photoperiod plays an essential role in regulating the annual activity of the testis and that the photoperiodic environmental conditions required for the activation of the LHRH system differ between the species. Similarly, correlations could be found between an increase in immunoreactivity of the vasopressinergic axons projecting to the external median eminence and the recrudescence of testicular activity.
利用免疫化学方法对分泌促肾上腺皮质激素释放激素（CRF）、生长抑素、催产素、血管加压素和促黄体生成素释放激素（LHRH）的下丘脑系统进行了表征，并研究了雪貂和水貂这两种年度繁殖周期光调节相反的物种中，这些系统的变化与睾丸活动复发之间的关系。在当前的研究条件下，CRF、生长抑素和催产素系统的免疫反应性在这两个物种中均未显示出显著变化。相反，在这两个物种中，LHRH系统的免疫反应性根据观察日期有很大差异。水貂在11月、雪貂在1月出现的分泌LHRH神经元数量和免疫反应性的增加，与先前的结果一致，即光周期在调节睾丸的年度活动中起重要作用，且激活LHRH系统所需的光周期环境条件在不同物种间存在差异。同样，投射到外侧正中隆起的血管加压素能轴突免疫反应性的增加与睾丸活动的复发之间也存在相关性。
