Kassem Hisham, Urits Ivan, Viswanath Omar, Kaye Alan D, Eskander Jonathan P
Anesthesiology and Perioperative Medicine, Mount Sinai Medical Center, Miami Beach, USA.
Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
Cureus. 2020 Dec 5;12(12):e11917. doi: 10.7759/cureus.11917.
The use of regional anesthetic techniques in the peri-operative period has increased as a means to improve analgesia and patient outcomes. Traditionally, various local anesthetics are used and addition of adjuncts such as epinephrine, clonidine, and dexamethasone has shown to prolong the block effect. There has been ongoing research to support the prolongation of a regional block with the addition of dexamethasone and dexmedetomidine (Dex-Dex), providing analgesia for multiple days. We present a case of a 35-year-old female who underwent an Achilles tendon repair with an adductor/popliteal nerve block. Both dexmedetomidine and dexamethasone were added to the local anesthetic mixture with substantial postoperative analgesic control. The patient also did not require any supplemental opioid medication. This case emphasizes the proposed synergistic effect of dexmedetomidine and dexamethasone when added to the local anesthesia injectate for lower extremity peripheral nerve blocks.
围手术期区域麻醉技术的应用有所增加,作为改善镇痛效果和患者预后的一种手段。传统上,会使用各种局部麻醉剂,添加肾上腺素、可乐定和地塞米松等辅助药物已显示可延长阻滞效果。一直在进行研究以支持通过添加地塞米松和右美托咪定(右美托咪定-地塞米松)来延长区域阻滞时间,从而提供多日镇痛。我们报告一例35岁女性患者,她接受了跟腱修复术,并采用了内收肌/腘神经阻滞。右美托咪定和地塞米松均添加到局部麻醉混合液中,术后镇痛效果良好。患者也无需任何补充性阿片类药物。该病例强调了右美托咪定和地塞米松添加到局部麻醉注射液中用于下肢周围神经阻滞时所提议的协同效应。