• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

安大略省的神经瘤与幻肢痛管理:靶向肌肉再支配的现状

Managing Neuroma and Phantom Limb Pain in Ontario: The Status of Targeted Muscle Reinnervation.

作者信息

Létourneau Sasha G, Hendry J Michael

机构信息

Queen's University School of Medicine, Kingston, Ontario, Canada.

Division of Plastic Surgery, Department of Surgery, Queen's University, Kingston, Ontario, Canada.

出版信息

Plast Reconstr Surg Glob Open. 2020 Dec 21;8(12):e3287. doi: 10.1097/GOX.0000000000003287. eCollection 2020 Dec.

DOI:10.1097/GOX.0000000000003287
PMID:33425599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7787323/
Abstract

UNLABELLED

Painful neuromas (PN) and phantom limb pain (PLP) are common following amputation and are unreliably treated, which impacts quality of life. Targeted muscle reinnervation (TMR) is a microsurgical technique that repairs the severed proximal nerve end to a redundant motor nerve in the amputated stump. Evidence supports TMR as effective in treating PN and PLP; however, its adoption has been slow. This study aimed to characterize: (1) the populations experiencing post-amputation PN/PLP; (2) current trends in managing PN/PLP; and (3) attitudes toward routine use of TMR to manage PN/PLP.

METHODS

A cross-sectional survey was distributed to all orthopedic surgeons, plastic surgeons, and physiatrists practicing in Ontario, via publicly available emails and specialty associations. Data were collected on demographics, experience with amputation, managing post-amputation pain, and attitudes toward routine use of TMR.

RESULTS

Sixty-six of 698 eligible participants submitted complete surveys (9.5% response rate). Respondents had a greater experience with surgical management of PN (71% PN versus 10% PLP). However, surgery was considered a 3rd-line option for PN and not an option for PLP in 57% and 59% of respondents, respectively. Thirty participants (45%) were unaware of TMR as an option, and only 8 respondents have currently incorporated TMR into their practice. Many (76%) would be willing to incorporate TMR into their practice as either an immediate or delayed surgical technique.

CONCLUSIONS

Despite its promise in managing post-amputation pain, awareness of TMR as a surgical option is generally poor. Several barriers to the widespread adoption of this technique are defined.

摘要

未标注

疼痛性神经瘤(PN)和幻肢痛(PLP)在截肢后很常见,且治疗效果不佳,这会影响生活质量。靶向肌肉再支配术(TMR)是一种显微外科技术,可将切断的近端神经末端修复到截肢残端的一条冗余运动神经上。有证据支持TMR在治疗PN和PLP方面有效;然而,其应用进展缓慢。本研究旨在描述:(1)经历截肢后PN/PLP的人群特征;(2)当前管理PN/PLP的趋势;(3)对常规使用TMR来管理PN/PLP的态度。

方法

通过公开可用的电子邮件和专业协会,向安大略省所有执业的骨科医生、整形外科医生和物理治疗师发放了一份横断面调查问卷。收集了有关人口统计学、截肢经验、管理截肢后疼痛以及对常规使用TMR的态度的数据。

结果

698名符合条件的参与者中有66人提交了完整的调查问卷(回复率为9.5%)。受访者对PN的手术管理经验更丰富(71%处理PN,而处理PLP的为10%)。然而,分别有57%和59%的受访者认为手术是PN的三线选择,而不是PLP的选择。30名参与者(4

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/ad06a2f33805/gox-8-e3287-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/faece1c5b5d9/gox-8-e3287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/556d9dadbadc/gox-8-e3287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/aa7976284f16/gox-8-e3287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/98c517ac54a8/gox-8-e3287-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/6e3f2eded5e8/gox-8-e3287-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/0018c9c184a0/gox-8-e3287-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/405d6f25f277/gox-8-e3287-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/ad06a2f33805/gox-8-e3287-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/faece1c5b5d9/gox-8-e3287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/556d9dadbadc/gox-8-e3287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/aa7976284f16/gox-8-e3287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/98c517ac54a8/gox-8-e3287-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/6e3f2eded5e8/gox-8-e3287-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/0018c9c184a0/gox-8-e3287-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/405d6f25f277/gox-8-e3287-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34aa/7787323/ad06a2f33805/gox-8-e3287-g008.jpg

相似文献

1
Managing Neuroma and Phantom Limb Pain in Ontario: The Status of Targeted Muscle Reinnervation.安大略省的神经瘤与幻肢痛管理:靶向肌肉再支配的现状
Plast Reconstr Surg Glob Open. 2020 Dec 21;8(12):e3287. doi: 10.1097/GOX.0000000000003287. eCollection 2020 Dec.
2
A consecutive series of targeted muscle reinnervation (TMR) cases for relief of neuroma and phantom limb pain: UK perspective.一系列连续的用于缓解神经瘤和幻肢痛的靶向肌肉再支配(TMR)病例:英国视角。
J Plast Reconstr Aesthet Surg. 2022 Mar;75(3):960-969. doi: 10.1016/j.bjps.2021.09.068. Epub 2021 Oct 22.
3
Targeted muscle reinnervation in managing post-amputation related pain: A systematic review and meta-analysis.靶向肌肉神经再支配治疗截肢后相关疼痛:系统评价和荟萃分析。
Pain Pract. 2023 Nov;23(8):922-932. doi: 10.1111/papr.13262. Epub 2023 Jun 26.
4
Targeted Muscle Reinnervation at the Time of Amputation Decreases Recurrent Symptomatic Neuroma Formation.截肢时的靶向肌肉神经再支配可减少复发性症状性神经瘤的形成。
Plast Reconstr Surg. 2024 Jan 1;153(1):154-163. doi: 10.1097/PRS.0000000000010692. Epub 2023 May 18.
5
Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation.在大肢体截肢时,通过靶向肌肉神经再支配对幻肢和残肢痛进行预防性治疗。
J Am Coll Surg. 2019 Mar;228(3):217-226. doi: 10.1016/j.jamcollsurg.2018.12.015. Epub 2019 Jan 8.
6
Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interfaces Versus Standard Management in the Treatment of Limb Amputation: A Systematic Review and Meta-Analysis.靶向肌肉再支配和再生周围神经接口与肢体截肢治疗中的标准管理对比:一项系统评价和荟萃分析
Plast Surg (Oakv). 2024 May;32(2):253-264. doi: 10.1177/22925503221107462. Epub 2022 Jun 16.
7
Targeted Muscle Reinnervation for Limb Amputation to Avoid Neuroma and Phantom Limb Pain in Patients Treated at a Pediatric Hospital.小儿医院治疗的肢体截肢患者采用靶向肌肉神经再支配术以避免神经瘤和幻肢痛
Plast Reconstr Surg Glob Open. 2023 Apr 13;11(4):e4944. doi: 10.1097/GOX.0000000000004944. eCollection 2023 Apr.
8
Targeted Muscle Reinnervation Treats Neuroma and Phantom Pain in Major Limb Amputees: A Randomized Clinical Trial.靶向肌肉神经再支配治疗主要肢体截肢患者的神经瘤和幻肢痛:一项随机临床试验。
Ann Surg. 2019 Aug;270(2):238-246. doi: 10.1097/SLA.0000000000003088.
9
Targeted Muscle Reinnervation at the Time of Upper-Extremity Amputation for the Treatment of Pain Severity and Symptoms.上肢截肢时的靶向肌肉神经再支配治疗疼痛严重程度和症状。
J Hand Surg Am. 2021 Jan;46(1):72.e1-72.e10. doi: 10.1016/j.jhsa.2020.08.014. Epub 2020 Oct 22.
10
Targeted muscle reinnervation: a brief history of a promising procedure for effective management of amputation pain.靶向肌肉神经再支配:一种有前途的有效管理截肢痛的方法的简史。
Wounds. 2023 Dec;35(12):E433-E438. doi: 10.25270/wnds/23079.

引用本文的文献

1
Curative and preemptive treatment of amputee pain by targeted muscle reinnervation: experience from a French military trauma center.通过靶向肌肉再支配对截肢者疼痛进行治疗性和预防性治疗:来自法国军事创伤中心的经验。
Eur J Trauma Emerg Surg. 2025 Jan 24;51(1):37. doi: 10.1007/s00068-024-02701-w.
2
Trigeminal Traumatic Neuroma: a Comprehensive Review of the Literature Based On a Rare Case.三叉神经创伤性神经瘤:基于罕见病例的文献综合回顾。
Curr Pain Headache Rep. 2022 Mar;26(3):219-233. doi: 10.1007/s11916-022-01018-w. Epub 2022 Feb 4.

本文引用的文献

1
Targeted Muscle Reinnervation: Outcomes in Treating Chronic Pain Secondary to Extremity Amputation and Phantom Limb Syndrome.靶向肌肉神经再支配:治疗四肢截肢和幻肢综合征引起的慢性疼痛的疗效。
J Reconstr Microsurg. 2020 May;36(4):235-240. doi: 10.1055/s-0039-1700559. Epub 2019 Nov 5.
2
Neuromas and postamputation pain.神经瘤和截肢后疼痛。
Pain. 2020 Jan;161(1):147-155. doi: 10.1097/j.pain.0000000000001705.
3
Recent advances in understanding and managing phantom limb pain.幻肢痛理解与管理的最新进展
F1000Res. 2019 Jul 23;8. doi: 10.12688/f1000research.19355.1. eCollection 2019.
4
Targeted muscle reinnervation in oncologic amputees: Early experience of a novel institutional protocol.肿瘤截肢患者的靶向肌肉神经再支配:一种新的机构方案的早期经验。
J Surg Oncol. 2019 Sep;120(3):348-358. doi: 10.1002/jso.25586. Epub 2019 Jun 13.
5
Surgery for Symptomatic Neuroma: Anatomic Distribution and Predictors of Secondary Surgery.症状性神经瘤手术:二次手术的解剖分布和预测因素。
Plast Reconstr Surg. 2019 Jun;143(6):1762-1771. doi: 10.1097/PRS.0000000000005664.
6
A national study of Veterans with major upper limb amputation: Survey methods, participants, and summary findings.一项针对上肢主要截肢退伍军人的全国性研究:调查方法、参与者和总结发现。
PLoS One. 2019 Mar 14;14(3):e0213578. doi: 10.1371/journal.pone.0213578. eCollection 2019.
7
Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation.在大肢体截肢时,通过靶向肌肉神经再支配对幻肢和残肢痛进行预防性治疗。
J Am Coll Surg. 2019 Mar;228(3):217-226. doi: 10.1016/j.jamcollsurg.2018.12.015. Epub 2019 Jan 8.
8
Targeted Muscle Reinnervation Technique in Below-Knee Amputation.靶向肌肉神经再支配技术在膝下截肢中的应用。
Plast Reconstr Surg. 2019 Jan;143(1):309-312. doi: 10.1097/PRS.0000000000005133.
9
Phantom limb pain: A literature review.幻肢痛:文献综述
Chin J Traumatol. 2018 Dec;21(6):366-368. doi: 10.1016/j.cjtee.2018.04.006. Epub 2018 Dec 4.
10
Surgical Algorithm for Neuroma Management: A Changing Treatment Paradigm.神经瘤治疗的手术算法:不断变化的治疗模式
Plast Reconstr Surg Glob Open. 2018 Oct 16;6(10):e1952. doi: 10.1097/GOX.0000000000001952. eCollection 2018 Oct.