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危及生命的血胸的院前自体输血

Prehospital autotransfusion in life-threatening hemothorax.

作者信息

Barriot P, Riou B, Viars P

机构信息

Service de Santé de la Brigade des Sapeurs Pompiers de Paris, France.

出版信息

Chest. 1988 Mar;93(3):522-6. doi: 10.1378/chest.93.3.522.

Abstract

Eighteen patients with life-threatening traumatic hemothorax received prehospital autotransfusion using a simple new device. During transfer to the hospital, they received 3.9 +/- 0.5 L of colloid fluid and 4.1 +/- 0.6 L of autotransfused blood, without anticoagulation. Hemorrhagic blood was not coagulable, had a hematocrit of 20 +/- 4 percent, few platelets, and low fibrinogen levels. Five patients died from irreversible hemorrhagic shock. Thirteen patients were alive upon admission to the hospital, underwent emergency surgery, and were discharged alive. During autotransfusion, hematocrit decreased from 24 +/- 3 to 19 +/- 3 percent, and systolic arterial pressure increased from 78 +/- 11 to 88 +/- 12 mm Hg. Upon admission to the hospital, platelet count was 90,800 +/- 21,400/cu mm, prothrombin time 48 +/- 3 percent, partial thromboplastin time 197 +/- 18 percent, plasma free hemoglobin levels 21 +/- 7 mg/100 ml, and serum potassium levels 3.6 +/- 0.5 mmol/L. No serious complication could be related to autotransfusion considered to be crucial to patients' survival. The preliminary results of this study suggest that autotransfusion might be developed in the prehospital setting since it appears simple and safe, and represents the only hope of survival for patients with life-threatening hemothorax.

摘要

18例危及生命的创伤性血胸患者使用一种简单的新设备进行了院前自体输血。在转往医院的过程中,他们接受了3.9±0.5升胶体液和4.1±0.6升自体回输血,未进行抗凝处理。出血血液不可凝固,血细胞比容为20±4%,血小板数量少,纤维蛋白原水平低。5例患者死于不可逆性失血性休克。13例患者入院时存活,接受了急诊手术,出院时也存活。在自体输血过程中,血细胞比容从24±3%降至19±3%,收缩动脉压从78±11毫米汞柱升至88±12毫米汞柱。入院时,血小板计数为90,800±21,400/立方毫米,凝血酶原时间为48±3%,部分凝血活酶时间为197±18%,血浆游离血红蛋白水平为21±7毫克/100毫升,血清钾水平为3.6±0.5毫摩尔/升。没有严重并发症与自体输血相关,自体输血被认为对患者的生存至关重要。这项研究的初步结果表明,院前自体输血可能会得到发展,因为它看起来简单且安全,是危及生命的血胸患者唯一的生存希望。

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