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肺部超声在非危重新冠肺炎患者评估中的应用。

Lung Ultrasound Integration in Assessment of Patients with Noncritical COVID-19.

机构信息

Emergency Department, General University Hospital of Alicante-ISABIAL, Alicante, Spain.

Clinical Medicine Department, University Miguel Hernández of Elche, Alicante, Spain.

出版信息

J Ultrasound Med. 2021 Oct;40(10):2203-2212. doi: 10.1002/jum.15613. Epub 2021 Jan 11.

Abstract

OBJECTIVES

Performing lung ultrasound during the clinical assessment of patients with suspicion of noncritical COVID-19 may increase the diagnostic rate of pulmonary involvement over other diagnostic techniques used in routine clinical practice. This study aims to compare complications (readmissions, emergency department [ED] visits, and length of outpatient follow-up) in the first 30 days after ED discharge in patients with confirmed COVID-19 who were managed with versus without lung ultrasound.

MATERIALS AND METHODS

Prospective, observational, analytical study in noncritical patients with confirmed respiratory disease due to SARS-CoV-2, assessed in the ED of a tertiary Spanish hospital in March and April 2020. We compared 2 cohorts, differentiated by the use of lung ultrasound as a diagnostic tool. Complications were assessed (hospital admissions, ED revisits and days of outpatient follow-up) at 30 days postdischarge.

RESULTS

Of the 88 included patients, 31% (n = 27) underwent an initial lung ultrasound, while 61 (68%) did not. In 82.5% of the patients evaluated with ultrasound, the most predominant areas affected were the posterobasal regions, in the form of focalized and confluent B-lines; 70.4% showed pleural irregularity in these same areas. Use of the lung ultrasound was associated with a greater probability of hospital admission (odds ratio 5.63, 95% confidence interval 3.31 to 9.57; p < 0.001). However, it was not significantly associated with mortality or short-term complications.

CONCLUSIONS

Lung ultrasound could identify noncritical patients with lung impairment due to SARS-CoV-2, in whom other tests used routinely show no abnormalities. However, it has not shown a prognostic value in these patients and could generate a higher percentage of hospital admissions. More studies are still needed to demonstrate the clear benefit of this use.

摘要

目的

在疑似非危重新冠肺炎患者的临床评估中进行肺部超声检查,可能会比常规临床实践中使用的其他诊断技术提高肺部受累的诊断率。本研究旨在比较经急诊(ED)确诊并出院的新冠肺炎患者中,使用与未使用肺部超声的患者在 ED 出院后 30 天内的并发症(再入院、ED 就诊和门诊随访时间)。

材料和方法

这是一项前瞻性、观察性、分析性研究,纳入了 2020 年 3 月至 4 月在西班牙一家三级医院 ED 就诊的非危重新冠肺炎患者。我们比较了两组患者,根据是否将肺部超声作为诊断工具进行分组。在出院后 30 天评估并发症(住院、ED 复诊和门诊随访时间)。

结果

在 88 例纳入患者中,31%(n=27)进行了初始肺部超声检查,而 61%(n=61)未进行。在接受超声评估的患者中,82.5%的患者最常见的受累区域为后基底区域,呈局灶性和融合性 B 线;在这些相同区域,70.4%的患者出现胸膜不规则。使用肺部超声与更高的住院概率相关(优势比 5.63,95%置信区间 3.31 至 9.57;p<0.001)。然而,它与死亡率或短期并发症无关。

结论

肺部超声可以识别出因 SARS-CoV-2 导致肺部受损的非危重新冠肺炎患者,而常规使用的其他检查方法并未显示异常。然而,它在这些患者中并没有显示出预后价值,可能会导致更高的住院率。仍需要更多的研究来证明这种应用的明确益处。

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