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L5-S1 节段间支撑对融合至骨盆的长节段固定是否重要?5 年分析。

Does Interbody Support at L5-S1 Matter in Long Fusions to the Pelvis?: A 5-year Analysis.

机构信息

Mayo Clinic Arizona, Phoenix, AZ.

Sonoran Spine Center, Tempe, AZ.

出版信息

Spine (Phila Pa 1976). 2021 Aug 1;46(15):1014-1019. doi: 10.1097/BRS.0000000000003937.

Abstract

STUDY DESIGN

Retrospective review of prospectively collected data.

OBJECTIVE

To determine if the addition of L5-S1 interbody support in long fusion deformity constructs is associated with superior long-term clinical and radiographic outcomes. To compare the 5-year clinical and radiographic outcomes and complications between long fusion constructs with L5-S1 interbody support versus posterolateral fusion (PLF) alone.

SUMMARY OF BACKGROUND DATA

Cadaveric biomechanical studies have suggested that an interbody fusion at L5-S1 is beneficial in long fusion constructs with sacropelvic fixation. However, there is limited data reflecting the superiority of interbody support augmentation in optimizing arthrodesis and deformity correction relative to PLF alone.

METHODS

Eighty-eight consecutive adults with spinal deformity who underwent at minimum T11-pelvis posterior pedicle screw instrumentation with 5-year follow-up were included. Two cohorts were compared based on technique used at the lumbosacral junction (L5-S1): (A) no interbody (PLF; n = 23), or (B) interbody support at L5-S1 (IB; n = 65). Radiographic measurements and clinical outcome measures were compared at multiple time points. Complications were recorded and compared.

RESULTS

No differences in baseline patient characteristics between cohorts. One nonunion occurred at L5-S1 in the PLF group (P = 0.091). Initial postop sagittal alignment was better in the IB group (PLF: 6.46 cm, IB: 2.48 cm, P = 0.007); however, this was not maintained over long-term follow-up. No significant differences in proximal junctional kyphosis (PLF: 7/23, IB: 9/65, P = 0.076). Proximal junctional failure was more frequent in the PLF group (PLF: 6/23, IB: 6/65, P = 0.043). No significant differences in complications were found. Both cohorts had improvement from baseline pain and functional scores.

CONCLUSION

There is no absolute long-term advantage for lumbar interbody support in adult spinal deformity patients undergoing spinal arthrodesis to the pelvis.Level of Evidence: 3.

摘要

研究设计

前瞻性收集数据的回顾性研究。

目的

确定在长节段融合畸形结构中增加 L5-S1 椎间支撑是否与更好的长期临床和影像学结果相关。比较 L5-S1 椎间支撑与单纯后外侧融合(PLF)的 5 年临床和影像学结果及并发症。

背景资料总结

尸体生物力学研究表明,在骨盆固定的长融合结构中,L5-S1 椎间融合是有益的。然而,相对于单纯 PLF,关于椎间支撑增强在优化融合和畸形矫正方面的优势的资料有限。

方法

共纳入 88 例接受至少 T11 骨盆后路椎弓根螺钉固定术且有 5 年随访的脊柱畸形成人患者。根据腰骶部(L5-S1)技术分为两组:(A)无椎间融合(PLF;n=23)或(B)L5-S1 椎间支撑(IB;n=65)。在多个时间点比较影像学测量和临床结果测量。记录并比较并发症。

结果

两组患者基线特征无差异。PLF 组有 1 例 L5-S1 不愈合(P=0.091)。IB 组术后即刻矢状位排列更好(PLF:6.46cm,IB:2.48cm,P=0.007);然而,这在长期随访中并未维持。近端交界性后凸(PLF:7/23,IB:9/65,P=0.076)无显著差异。PLF 组近端交界性失败更常见(PLF:6/23,IB:6/65,P=0.043)。两组并发症无显著差异。两组患者的疼痛和功能评分均较基线有所改善。

结论

在接受骨盆融合的成人脊柱畸形患者中,腰椎椎间支撑并没有绝对的长期优势。

证据等级

3。

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