Faculty of Health Sciences, University of Malta, Malta.
National Blood Transfusion Service, Malta.
Lab Med. 2021 Jul 1;52(4):364-368. doi: 10.1093/labmed/lmaa102.
Hemoglobin (Hb) evaluation by point-of-care testing (POCT) identifies borderline or anaemic asymptomatic blood donors. Although quality control checks confirm that this device is fit for use, it is still not clear whether the analyser is performing effectively. A protocol comparing the POCT EKF Diagnostics with the Sysmex XN-550 automated cell counter (ACC) has been designed.
Various scenarios of Hb measurements from the ACC and the POCT device are compared using the Spearman correlation and Intraclass correlation. The Bland-Altman method was used to analyse the level of agreement between the two devices.
Correlation between the two devices was best observed in the venous vs venous blood scenario.
The POCT device overestimates the Hb levels in capillary blood, meaning that Hb requirements should be adjusted and when feasible testing repeated on venous blood using an ACC. Furthermore, it is suggested thar each Facility determine their own Hb threshold.
通过即时检测（POCT）对血红蛋白（Hb）进行评估，可以发现边缘性或贫血无症状献血者。尽管质量控制检查证实该设备适合使用，但仍不清楚该分析仪是否能有效运行。现已设计了一种比较 POCT EKF Diagnostics 与 Sysmex XN-550 自动化细胞计数器（ACC）的方案。
使用 Spearman 相关和组内相关比较 ACC 和 POCT 设备的各种 Hb 测量情况。采用 Bland-Altman 法分析两种设备之间的一致性水平。
在静脉血与静脉血的情况下，两种设备的相关性最佳。
POCT 设备会高估毛细血管血中的 Hb 水平，这意味着应调整 Hb 要求，并在可行的情况下使用 ACC 对静脉血进行重复检测。此外，建议每个机构确定自己的 Hb 阈值。
