Zhongshan Hospital Affiliated to Guangzhou TCM University, Zhongshan, Guangdong Province.
The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, P.R. China.
Medicine (Baltimore). 2021 Jan 8;100(1):e23964. doi: 10.1097/MD.0000000000023964.
Kidney stone is one of the urinary system diseases with a high incidence. In this study, we will evaluate the effectiveness and safety of Sun tip-flexible ureterorenoscope treating patients with kidney stone.
English and Chinese literature about Sun tip-flexible ureterorenoscope treatment for kidney stones published before October 31, 2020 will be systematic searched in PubMed, Embase, Web of Science, Cochrane Library, Open Grey, Clinicaltrials.gov, Chinese Clinical Trial Registry, WANFANG, VIP Chinese Science and Technology Journal Database, CNKI, Chinese biomedical document service system (SinoMed). Only randomized controlled trials (RCTs) of patients with kidney stones will be included. Literature screening, data extraction, and the assessment of risk of bias will be independently conducted by 2 reviewers, and the 3rd reviewer will be consulted if any different opinions existed. Systematic review and meta-analysis will be produced by RevMan 5.3 and Stata 14.0. This protocol reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) statement, and we will report the systematic review by following the PRISMA statement.
The current study is a protocol for systematic review and meta-analysis without results, and data analysis will be carried out after the protocol. We will share our findings in the fourth quarter of 2021.
This study will provide recommendations for the effectiveness and safety of Sun tip-flexible ureterorenoscope for patients with kidney stones (KS), which may help to guide clinician.
Ethical approval is not required as the review is a secondary study based on published literature. The results of the study will be published in peer-reviewed publications and disseminated electronically or in print.
INPLASY2020110099.
肾结石是一种发病率较高的泌尿系统疾病。本研究旨在评估 Sun tip 输尿管软镜治疗肾结石患者的有效性和安全性。
系统检索 PubMed、Embase、Web of Science、Cochrane 图书馆、Open Grey、Clinicaltrials.gov、中国临床试验注册中心、万方、维普中文科技期刊数据库、中国知网、中国生物医学文献服务系统（SinoMed）中截至 2020 年 10 月 31 日发表的关于 Sun tip 输尿管软镜治疗肾结石的英文和中文文献。仅纳入肾结石患者的随机对照试验（RCT）。由 2 名评价员独立进行文献筛选、数据提取和偏倚风险评估，如果存在分歧，则由第 3 名评价员协商解决。采用 RevMan 5.3 和 Stata 14.0 进行系统评价和荟萃分析。本研究方案按照系统评价和荟萃分析优先报告条目（PRISMA-P）声明进行报告，并将按照 PRISMA 声明报告系统评价。
本研究是一项系统评价和荟萃分析的方案，目前尚无结果，将在方案制定后进行数据分析。我们将于 2021 年第四季度公布研究结果。
本研究将为 Sun tip 输尿管软镜治疗肾结石患者的有效性和安全性提供建议，有助于指导临床医生。
本研究为基于已发表文献的二次研究，无需伦理批准。研究结果将发表在同行评议的出版物中，并通过电子或印刷方式传播。
INPLASY2020110099。
