Liu Min, Liu Dongying, Hong Peipei, Qiu Xianliang, Chen Qiu
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Medicine (Baltimore). 2020 May 22;99(21):e20379. doi: 10.1097/MD.0000000000020379.
Osteoporosis (OP) and related fragility fractures are a significant public health problem which leads to pain, disability, loss function of independence, considerable complications and increased mortality. Exercise training is the only alternative strategy to improve multiple skeletal and fall risk factors simultaneously. Wuqinxi is 1 of the Chinese mind-body exercises using to improve physical and mental health and fight against diseases for thousands of years. Our study aims to systematically review the existing literature to further explore the efficacy and safety of Wuqinxi in the prevention and treatment of osteopenia and OP.
The following electronic databases (PubMed, Science Citation Index, Embase (Ovid) database, the Cochrane Library, the China National Knowledge Infrastructure, the China Biology Medicine disc, the China Science and Technology Journal Database, the Wan fang Database, ClinicalTrials.gov and the Chinese Clinical Trial Registry Platform) will be searched from the beginning to 1 June 2020. Only randomized controlled trials will be enrolled, in which the intervention group must include a form of Wuqinxi, while the control group can involve other conventional treatment or no intervention. The potential outcome measures will include bone mineral density values, bone turnover markers, fragility fractures, quality of life, pain scores, and adverse events. The Cochrane risk of bias assessment tool will be used to assess the risk of bias in each study.
The current study is a protocol for systematic review and meta-analysis without results, and data analysis will be carried out after the protocol. We will share our findings in the third quarter of 2021.
This review aims to evaluate up-to-date evidence of Wuqinxi for bone health in English or Chinese language studies, and explore whether Wuqinxi can be used as an adjuvant treatment for osteoporosis and osteopenia.
Ethical approval is not required as the review is a secondary study based on published literature. The results of the study will be published in peer-reviewed publications and disseminated electronically or in print.
INPLASY202040135.
骨质疏松症（OP）及相关脆性骨折是一个重大的公共卫生问题，会导致疼痛、残疾、丧失独立生活能力、出现相当多的并发症并增加死亡率。运动训练是唯一能同时改善多种骨骼和跌倒风险因素的替代策略。五禽戏是中国传统的身心锻炼方式之一，数千年来一直用于改善身心健康和对抗疾病。我们的研究旨在系统回顾现有文献，以进一步探讨五禽戏在预防和治疗骨质减少和骨质疏松症方面的疗效和安全性。
将检索以下电子数据库（PubMed、科学引文索引、Embase（Ovid）数据库、Cochrane图书馆、中国知网、中国生物医学光盘数据库、中国科技期刊数据库、万方数据库、ClinicalTrials.gov和中国临床试验注册平台），检索时间从建库至2020年6月1日。仅纳入随机对照试验，其中干预组必须包含某种形式的五禽戏，而对照组可采用其他传统治疗或不进行干预。潜在的结局指标将包括骨密度值、骨转换标志物、脆性骨折、生活质量、疼痛评分和不良事件。将使用Cochrane偏倚风险评估工具评估每项研究的偏倚风险。
本研究是一项系统评价和荟萃分析的方案，目前尚无结果，将在方案制定后进行数据分析。我们将在2021年第三季度分享研究结果。
本综述旨在评估中英文研究中关于五禽戏对骨骼健康影响的最新证据，并探讨五禽戏是否可作为骨质疏松症和骨质减少的辅助治疗方法。
由于本综述是基于已发表文献的二次研究，因此无需伦理批准。研究结果将发表在同行评审的出版物上，并以电子或印刷形式传播。
INPLASY202040135
